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PHARMACEUTICAL FORMULATION OF PALBOCICLIB AND A PREPARATION METHOD THEREOF

  • US 20170281631A1
  • Filed: 06/05/2017
  • Published: 10/05/2017
  • Est. Priority Date: 03/29/2016
  • Status: Active Grant
First Claim
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1. A pharmaceutical formulation of palbociclib, comprising a palbociclib free base or a pharmaceutically acceptable salt thereof and an acidic auxiliary material, wherein the acidic auxiliary material is one or more selected from the group consisting of tartaric acid, fumaric acid, succinic acid, citric acid, lactic acid and malic acid, and wherein a mass ratio of the acidic auxiliary material to palbociclib is from 0.2:

  • 1 to 5;

    1.

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