IMPLANTABLE CELLULAR AND BIOTHERAPEUTIC AGENT DELIVERY CANISTER
First Claim
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1. (1) An implantable canister for containing and delivering metabolically active agents, comprising:
- (a) a metallic shell configured to possess nanoscale through-porous membrane characteristics, the shell defining a first major surface and a second major surface;
(b) an interior chamber between the first major surface and second major surface; and
(c) means allowing fluid communication with the interior chamber.
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Abstract
The invention relates to a metallic, nanoporous canister used to encapsulate cellular and/or biotherapeutic agents. The device is biocompatible and functions to wholly isolate a therapeutically active agent and/or cells therein. Their implantation, and survival in vivo, permits the local or systemic diffusion of their encapsulated cellular and/or biomolecular and therapeutics factors with the potential to promote repair of damaged or degenerated tissues in mammalian hosts, primarily humans.
4 Citations
20 Claims
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1. (1) An implantable canister for containing and delivering metabolically active agents, comprising:
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(a) a metallic shell configured to possess nanoscale through-porous membrane characteristics, the shell defining a first major surface and a second major surface; (b) an interior chamber between the first major surface and second major surface; and (c) means allowing fluid communication with the interior chamber. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 13)
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12. (12) An implantable canister for containing and delivering metabolically active agents, comprising:
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(a) a metallic shell configured to possess nanoscale through-porous membrane characteristics, the shell defining a first major surface and a second major surface and a side surface separating the first major surface and the second major surface; (b) an interior chamber between the first major surface and second major surface; and (c) means allowing fluid communication with the interior chamber. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20)
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Specification