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METHOD OF PRODUCING TRANSDERMAL ABSORPTION SHEET

  • US 20170333342A1
  • Filed: 05/22/2017
  • Published: 11/23/2017
  • Est. Priority Date: 05/23/2016
  • Status: Active Grant
First Claim
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1. A method of producing a transdermal absorption sheet comprising, in this order:

  • a polymer solution filling step of filling needle-like recessed portions on a mold having the needle-like recessed portions arranged two-dimensionally with a polymer solution;

    a polymer solution drying step of drying the polymer solution filling the needle-like recessed portions to form a polymer layer; and

    a peeling-off step of peeling off the polymer layer from the mold,wherein in the polymer solution drying step, low rate drying conditions are set in a concentration range in which an average solid content concentration of the polymer solution is 70 wt % or more and 80 wt % or less in terms of weight percent, andwhen a constant drying rate of water is used as an index, in the concentration range in which the average solid content concentration of the polymer solution is 70 wt % or more and 80 wt % or less in terms of weight percent, the constant drying rate is set to be lower than a maximum value of a constant drying rate under drying conditions in a concentration range in which the average solid content concentration of the polymer solution is less than 70 wt % and more than 80 wt % in terms of weight percent.

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