RENAL THERAPY MACHINE AND SYSTEM INCLUDING A PRIMING SEQUENCE

• US 20170333612A1
• Filed: 08/04/2017
• Published: 11/23/2017
• Est. Priority Date: 10/24/2007
• Status: Active Grant

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Inventors: Childers, Robert W., Kelly, Thomas D., Roger, Rodolfo
• Granted Patent: US 9,925,320 B2
• Time in Patent Office: Days
• CPC Class Codes: A61M 1/14 Dialysis systems; Artificial kidneys; Blood oxygenators semi-permeable membranes characterised by the material, manufacturing processes therefor B01D71/00 ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
• CPC Class Codes: A61M 1/1524 the interface providing means for actuating on functional elements of the cassette, e.g. plungers
• CPC Class Codes: A61M 1/153 the cassette being adapted for heating or cooling the treating fluid, e.g. the dialysate or the treating gas
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1561 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/15625 the reservoirs acting as balance chambers
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1601 Control or regulation
• CPC Class Codes: A61M 1/1605 Physical characteristics of the dialysate fluid
• CPC Class Codes: A61M 1/1621 Constructional aspects thereof semi-permeable membranes for separation processes characterised by their properties B01D69/00; semi permeable membranes characterised by their material B01D71/00
• CPC Class Codes: A61M 1/1635 with volume chamber balancing devices between used and fresh dialysis fluid
• CPC Class Codes: A61M 1/1649 with pulsatile dialysis fluid flow
• CPC Class Codes: A61M 1/166 Heating for sterilisation A61M1/1686
• CPC Class Codes: A61M 1/168 Sterilisation or cleaning before or after use
• CPC Class Codes: A61M 1/1686 by heat
• CPC Class Codes: A61M 1/1688 with recirculation of the sterilising fluid
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/281 Instillation other than by gravity
• CPC Class Codes: A61M 1/3465 using dialysate as substitution fluid
• CPC Class Codes: A61M 1/362227 : the interface providing means for actuating on functional elements of the cassette, e.g. plungers
• CPC Class Codes: A61M 1/36225 : with blood pumping means or components thereof
• CPC Class Codes: A61M 1/362261 : at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/362262 : Details of incorporated reservoirs
• CPC Class Codes: A61M 1/362265 : Details of valves
• CPC Class Codes: A61M 1/3643 : Priming, rinsing before or after use
• CPC Class Codes: A61M 1/3644 : Mode of operation
• CPC Class Codes: A61M 1/3649 : using dialysate as priming or rinsing liquid
• CPC Class Codes: A61M 1/3652 : using gas, e.g. air
• CPC Class Codes: A61M 2205/128 : with incorporated valves
• CPC Class Codes: A61M 2205/14 : Detection of the presence or absence of a tube, a connector or a container in an apparatus
• CPC Class Codes: A61M 2205/3313 : used specific wavelengths
• CPC Class Codes: A61M 2205/3331 : Pressure; Flow
• CPC Class Codes: A61M 2205/3334 : Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/3344 : Measuring or controlling pressure at the body treatment site
• CPC Class Codes: A61M 2205/3379 : Masses, volumes, levels of fluids in reservoirs, flow rates
• CPC Class Codes: A61M 2205/6036 : characterised by physical shape, e.g. array of activating switches
• CPC Class Codes: B01D 61/244 : comprising multiple dialysis steps
• CPC Class Codes: B01D 61/30 : Accessories; Auxiliary operation
• CPC Class Codes: Y10T 137/0396 : Involving pressure control
• CPC Class Codes: Y10T 137/87893 : With fluid actuator
• CPC Class Codes: Y10T 29/49826 : Assembling or joining

Abstract

A renal therapy machine includes a blood filter including a plurality of porous fibers; a blood circuit in communication with the blood filter; and a dialysate circuit in communication with the blood filter and operable with at least one pump, wherein the renal therapy machine is configured to perform a priming sequence in which a physiologically compatible solution, other than dialysate, primes the blood circuit and is flowed within the fibers and through pores in the fibers of the blood filter, and the pump of the dialysate circuit vents air from the blood filter into the dialysate circuit.

Claims

1. A renal therapy machine comprising:

a blood filter including a plurality of porous fibers;

a blood circuit in communication with the blood filter; and

a dialysate circuit in communication with the blood filter and operable with at least one pump,

wherein the renal therapy machine is configured to perform a priming sequence in which a physiologically compatible solution, other than dialysate, primes the blood circuit and is flowed within the fibers and through pores in the fibers of the blood filter, and the pump of the dialysate circuit vents air from the blood filter into the dialysate circuit.

2. The renal therapy machine of claim 1, wherein the pump operable with the dialysate circuit is a spent dialysate pump.

3. The renal therapy machine of claim 1, wherein the physiologically compatible solution, other than dialysate, is flowed through pores in the fibers of the blood filter and fills a housing of the blood filter holding the porous fibers.

4. The renal therapy machine of claim 1, wherein the physiologically compatible solution, other than dialysate, is flowed through the pores in the fibers of the blood filter and into the dialysate circuit.

5. The renal therapy machine of claim 4, wherein the physiologically compatible solution, other than dialysate, flowed into the dialysate circuit purges air from the dialysate circuit.

6. The renal therapy machine of claim 5, wherein the dialysate circuit is additionally primed using dialysate.

7. The renal therapy machine of claim 1, wherein the dialysate circuit is primed using dialysate.

8. The renal therapy machine of claim 1, wherein the blood circuit is primed using a blood pump and at least one valve operable with the blood circuit.

9. The renal therapy machine of claim 1, wherein the physiologically compatible solution, other than dialysate, includes saline.

10. A renal therapy machine comprising:

a blood filter including a housing holding a plurality of porous fibers;

a blood circuit in communication with the blood filter and operable with a blood pump; and

a dialysate circuit in communication with the blood filter and operable with at least one pump,

wherein the renal therapy machine is configured to perform a priming sequence in which a physiologically compatible solution, other than dialysate, is pumped by the blood pump to prime the blood circuit, and to flow within the fibers and through pores in the fibers of the blood filter, and wherein the pump operable with the dialysate circuit pulls physiologically compatible solution, other than dialysate, into the housing of the blood filter.

11. The renal therapy machine of claim 10, wherein the physiologically compatible solution, other than dialysate, is flowed through the pores in the fibers of the blood filter and into the dialysate circuit.

12. The renal therapy machine of claim 10, wherein the pump operable with the dialysate circuit pulls the physiologically compatible solution, other than dialysate, through the pores in the fibers of the blood filter and into the dialysate circuit.

13. The renal therapy machine of claim 10, wherein the pump operable with the dialysate circuit is a spent dialysate pump.

14. The renal therapy machine of claim 10, wherein the blood pump pumps in multiple directions to prime the blood circuit.

15. A renal therapy machine comprising:

a blood filter;

a blood circuit in communication with the blood filter; and

a dialysate circuit in communication with the blood filter and including a balancing structure forming a fresh dialysate circuit side between a fresh dialysate source and a fresh fluid inlet to the blood filter and a spent dialysate circuit side between a dialysate outlet of the blood filter and a drain,

wherein the renal therapy machine is configured to perform a priming sequence in which (i) a physiologically compatible solution, other than dialysate, is used to prime the blood circuit and at least a portion of the spent dialysate circuit side of the dialysate circuit formed by the balancing structure and (ii) dialysate is used to prime the fresh dialysate circuit side of the dialysate circuit formed by the balancing structure.

16. The renal therapy machine of claim 15, wherein the dialysate used to prime the fresh dialysate circuit side of the dialysate circuit formed by the balancing structure is fresh dialysate from the fresh dialysate source.

17. The renal therapy machine of claim 15, wherein a pump operable with the spent dialysate circuit side pulls the physiologically compatible solution, other than dialysate, from the blood filter and into the spent dialysate circuit side formed by the balancing structure.

18. The renal therapy machine of claim 17, wherein the pump operable with the spent dialysate circuit side also pushes the physiologically compatible solution, other than dialysate, to the balancing structure, causing fresh dialysate to flow along the fresh dialysate circuit side from the balancing structure to the blood filter.

19. The renal therapy machine of claim 15, wherein a fresh dialysate pump operable with the fresh dialysate circuit side pulls fresh dialysate from the fresh dialysate source into the fresh dialysate circuit side formed by the balancing structure.

20. The renal therapy machine of claim 19, wherein the fresh dialysate pump also pushes the fresh dialysate to the balancing structure, causing the physiologically compatible solution, other than dialysate, to flow along the spent dialysate circuit side, from the balancing structure to the drain.