Method and System for Image Registration Using an Intelligent Artificial Agent
First Claim
1. A method for intelligent artificial agent based registration of medical images, comprising:
- determining a current state observation of an artificial agent based on a plurality of medical images and current transformation parameters;
calculating action-values for a plurality of actions available to the artificial agent based on the current state observation using a machine learning based model trained based on a plurality of registered training images, wherein the plurality of actions correspond to predetermined adjustments of the transformation parameters;
selecting an action having a highest action-value from the plurality of actions and adjusting the transformation parameters by the predetermined adjustment corresponding to the selected action;
repeating the determining, calculating, and selecting steps for a plurality of iterations; and
registering the plurality of medical images using final transformation parameters resulting from the plurality of iterations.
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Abstract
Methods and systems for image registration using an intelligent artificial agent are disclosed. In an intelligent artificial agent based registration method, a current state observation of an artificial agent is determined based on the medical images to be registered and current transformation parameters. Action-values are calculated for a plurality of actions available to the artificial agent based on the current state observation using a machine learning based model, such as a trained deep neural network (DNN). The actions correspond to predetermined adjustments of the transformation parameters. An action having a highest action-value is selected from the plurality of actions and the transformation parameters are adjusted by the predetermined adjustment corresponding to the selected action. The determining, calculating, and selecting steps are repeated for a plurality of iterations, and the medical images are registered using final transformation parameters resulting from the plurality of iterations.
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Citations
39 Claims
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1. A method for intelligent artificial agent based registration of medical images, comprising:
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determining a current state observation of an artificial agent based on a plurality of medical images and current transformation parameters; calculating action-values for a plurality of actions available to the artificial agent based on the current state observation using a machine learning based model trained based on a plurality of registered training images, wherein the plurality of actions correspond to predetermined adjustments of the transformation parameters; selecting an action having a highest action-value from the plurality of actions and adjusting the transformation parameters by the predetermined adjustment corresponding to the selected action; repeating the determining, calculating, and selecting steps for a plurality of iterations; and registering the plurality of medical images using final transformation parameters resulting from the plurality of iterations. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. An apparatus for intelligent artificial agent based registration of medical images, comprising:
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a processor; and a memory storing computer program instructions, which when executed by the processor cause the processor to perform operations comprising; determining a current state observation of an artificial agent based on a plurality of medical images and current transformation parameters; calculating action-values for a plurality of actions available to the artificial agent based on the current state observation using a machine learning based model trained based on a plurality of registered training images, wherein the plurality of actions correspond to predetermined adjustments of the transformation parameters; selecting an action having a highest action-value from the plurality of actions and adjusting the transformation parameters by the predetermined adjustment corresponding to the selected action; repeating the determining, calculating, and selecting operations for a plurality of iterations; and registering the plurality of medical images using final transformation parameters resulting from the plurality of iterations. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28, 29)
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30. A non-transitory computer readable medium storing computer program instructions for intelligent artificial agent based registration of medical images, the computer program instructions defining operations comprising:
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determining a current state observation of an artificial agent based on a plurality of medical images and current transformation parameters; calculating action-values for a plurality of actions available to the artificial agent based on the current state observation using a machine learning based model trained based on a plurality of registered training images, wherein the plurality of actions correspond to predetermined adjustments of the transformation parameters; selecting an action having a highest action-value from the plurality of actions and adjusting the transformation parameters by the predetermined adjustment corresponding to the selected action; repeating the determining, calculating, and selecting operations for a plurality of iterations; and registering the plurality of medical images using final transformation parameters resulting from the plurality of iterations. - View Dependent Claims (31, 32, 33, 34, 35, 36, 37, 38, 39)
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Specification