CALIBRATION TECHNIQUES FOR A CONTINUOUS ANALYTE SENSOR

• US 20170340253A1
• Filed: 08/17/2017
• Published: 11/30/2017
• Est. Priority Date: 12/05/2003
• Status: Active Grant

• Current Assignee: DexCom Incorporated
• Original Assignee: DexCom Incorporated
• Inventors: Kamath, Apurv Ullas, Simpson, Peter C., Brauker, James H., Goode, JR., Paul V.
• Granted Patent: US 10,188,333 B2
• Time in Patent Office: Days
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: B33Y 80/00 Products made by additive manufacturing

Abstract

Disclosed herein are systems and methods for calibrating a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes one or more electrodes to measure an additional analyte. Such measurements may provide a baseline or sensitivity measurement for use in calibrating the sensor. Furthermore, baseline and/or sensitivity measurements may be used to trigger events such as digital filtering of data or suspending display of data.

Claims

1-15. -15. (canceled)

16. A system for continuous glucose sensing, the system comprising:

an implantable continuous glucose sensor configured to generate sensor data associated with glucose concentration in a host; and

sensor electronics comprising a process for executing computer program code stored in a memory to cause the sensor electronics to;

apply a voltage to the implantable continuous glucose sensor,

switch the voltage applied to the implantable continuous glucose sensor,

measure a signal response of the electrochemical glucose sensor responsive to a change in the voltage applied, wherein the signal response is associated with a sensitivity change of the implantable continuous glucose sensor,

calibrate the sensor data, wherein the calibrating accounts for the sensitivity change, and

generate at least one glucose concentration value based on the calibrated sensor data.