APPARATUS AND METHOD FOR PERFORMING NUCLEIC ACID ANALYSIS
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Abstract
The present invention relates to optical confinements, methods of preparing and methods of using them for analyzing molecules and/or monitoring chemical reactions. The apparatus and methods embodied in the present invention are particularly useful for high-throughput and low-cost single-molecular analysis.
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Citations
49 Claims
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1-29. -29. (canceled)
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30. A method of correcting sequence errors in a single molecule nucleic acid sequencing reaction, the method comprising:
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a) subjecting a nucleic acid molecule to a single molecule nucleic acid sequencing reaction to obtain redundant sequence reads for a nucleic acid segment of interest in the nucleic acid molecule; and b) analyzing the redundant sequence reads to correct an error in at least one of the redundant sequence reads for the nucleic acid segment of interest. - View Dependent Claims (31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49)
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Specification