Methods, Devices, Kits and Compositions For Detecting Roundworm, Whipworm and Hookworm

• US 20170343544A1
• Filed: 07/18/2017
• Published: 11/30/2017
• Est. Priority Date: 06/15/2007
• Status: Abandoned Application

• Current Assignee: Monsanto Company (Bayer AG), IDEXX Laboratories Incorporated
• Original Assignee: Monsanto Company (Bayer AG), IDEXX Laboratories Incorporated
• Inventors: ELSEMORE, David Allen, GENG, Jinming, FLYNN, Laurie A., CRAWFORD, Michael
• Application Number:
  US15/652,527
• Publication Number:
  US 20170343544A1
• Time in Patent Office: Days
• CPC Class Codes: G01N 2333/43526 from worms
• CPC Class Codes: G01N 2333/4353 from nematodes
• CPC Class Codes: G01N 2469/10 Detection of antigens from microorganism in sample from host
• CPC Class Codes: G01N 33/5308 for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
• CPC Class Codes: G01N 33/56966 Animal cells
• CPC Class Codes: G01N 33/6893 related to diseases not provided for elsewhere

Abstract

Methods, devices, kits and compositions for detecting the presence or absence of one or more helminthic coproantigens in a sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm, whipworm and/or hookworm in a fecal sample from a mammal and may also be able to distinguish between one or more helminth infections. Confirmation of the presence or absence of roundworm, whipworm and/or hookworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.

Claims

1. A device for detecting the presence or absence of one or more helminthic antigens from a sample;

the device comprising a solid support, wherein the solid support has immobilized thereon at least two antibodies selected from the group consisting of;

(a) a first antibody capable of specifically binding a roundworm coproantigen, but not a whipworm or hookworm coproantigen;

(b) a second antibody capable of specifically binding a whipworm coproantigen, but not a roundworm or hookworm coproantigen; and

(c) a third antibody capable of specifically binding a hookworm coproantigen, but not a whipworm or hookworm coproantigen.

2-61. -61. (canceled)