Vessel Occluder

• US 20170354421A1
• Filed: 06/09/2017
• Published: 12/14/2017
• Est. Priority Date: 06/10/2016
• Status: Active Grant

• Current Assignee: Terumo Corporation
• Original Assignee: Microvention Incorporated (Terumo Corporation)
• Inventors: Maguire, Shannon, Liang, Jessica, Beuthin, Wendy Graczyk, Luong-Uhl, Tin, Soliman, Peter
• Granted Patent: US 10,470,773 B2
• Time in Patent Office: Days
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 17/12159 Solid plugs; being solid before insertion
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12177 comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
• CPC Class Codes: A61B 2017/00575 for closure at remote site, e.g. closing atrial septum defects
• CPC Class Codes: A61B 2017/00592 Elastic or resilient implements
• CPC Class Codes: A61B 2017/00597 Implements comprising a membrane
• CPC Class Codes: A61B 2017/00623 Introducing or retrieving devices therefor
• CPC Class Codes: A61B 2017/12068 detachable by heat
• CPC Class Codes: A61B 2017/1209 detachable by electrical current or potential, e.g. electroactive polymer
• CPC Class Codes: A61B 2090/3966 Radiopaque markers visible in an X-ray image

Abstract

A vessel occluder used to occlude blood flow within the vasculature is described. The vessel occluder can include an expandable mesh portion having a flexible membrane that expands within a cavity of the expandable mesh portion. When expanded, the flexible membrane blocks blood passage through the mesh portion.

Claims

1. A vascular plug for treating a patient, comprising:

an elongated body;

a mesh portion fixed to a distal end of said elongated body;

said mesh portion having a radially compressed configuration and a radially expanded configuration when unconstrained; and

,

a membrane fixed within an interior cavity of said mesh portion;

said membrane being expandable within said interior cavity, thereby blocking blood passage through said mesh portion.

2. The vascular plug of claim 1, further comprising a support frame fixed within said interior cavity of said mesh portion and connected to said membrane.

3. The vascular plug of claim 2, wherein said support frame is configured to expand said membrane when said mesh portion is in said radially expanded configuration.

4. The vascular plug of claim 3, wherein said support frame is connected to a distal end of said mesh portion and to a proximal end of said mesh portion.

5. The vascular plug of claim 4, wherein said support frame further comprises a ring portion that expands to an orientation that is perpendicular to an axis between said proximal end and said distal end of said mesh portion.

6. The vascular plug of claim 2, wherein said membrane further comprises a laminating layer disposed over said membrane and said support frame.

7. The vascular plug of claim 6, wherein said membrane comprises a first layer of PET and said laminating layer comprises a second layer of ePTFE.

8. The vascular plug of claim 2, wherein said membrane is connected to said support frame via metal fibers, polymer fibers, or adhesives.

9. The vascular plug of claim 1, wherein said elongated body further comprises a tether attached to said mesh portion and a heater coil configured to break said tether to release said mesh portion within a patient.

10. The vascular plug of claim 1, wherein said elongated body further comprises a microcoil that is distally advanceable into said interior cavity of said mesh portion.

11. The vascular plug of claim 1, wherein said membrane has a circular shape.

12. The vascular plug of claim 1, wherein said membrane comprises a plurality of overlapping shapes.

13. The vascular plug of claim 1, wherein said radially expanded configuration forms a spherical shape, an oval shape, or a distally-facing concave shape.

14. The vascular plug of claim 1, wherein said membrane expands within said interior cavity of said mesh portion at a non-perpendicular angle relative to an axis of said elongated body.

15. A vascular plug for treating a patient, comprising:

An elongated pusher;

a mesh portion fixed to a distal end of said elongated pusher;

said mesh portion expanding between a radially compressed configuration and a radially expanded configuration; and

,

a membrane fixed within an interior cavity of said mesh portion;

said membrane being expandable within said interior cavity such that it creates a blockage within said mesh portion.

16. The vascular plug of claim 15, further comprising one or more wires positioned in said interior cavity of said mesh portion and being connected to said membrane so as to expand said membrane when said mesh portion is in said radially expanded configuration.

17. The vascular plug of claim 16, wherein said membrane further comprises a layer of material extending around a portion of said one or more wires.

18. The vascular plug of claim 16, wherein said elongated pusher further comprises a tether connected to said mesh portion and selectively breakable via a heater coil near a distal end of said elongated pusher.

19. A method of creating a blockage within a patient, comprising:

advancing an elongated body within a patient;

deploying a mesh portion at a distal end of said elongated body;

expanding said mesh portion to a radially expanded configuration;

expanding a membrane within a cavity of said mesh portion; and

,

detaching said mesh portion from said elongated body.