Arrays for Longitudinal Delivery of TTFields to a Body
First Claim
1. An apparatus for treating a target region in a subject'"'"'s body with TTFields, the target region being located in a portion of the subject'"'"'s body that has a longitudinal axis, the apparatus comprising:
- a first set of one or more capacitively coupled electrodes;
a first substrate configured to hold the first set of one or more electrodes against the subject'"'"'s body so that the first set of one or more electrodes surrounds a first part of the subject'"'"'s body at a position that is longitudinally prior to the target region;
a second set of one or more capacitively coupled electrodes;
a second substrate configured to hold the second set of one or more electrodes against the subject'"'"'s body so that the second set of one or more electrodes surrounds a second part of the subject'"'"'s body at a position that is longitudinally subsequent to the target region;
a third set of one or more capacitively coupled electrodes;
a third substrate configured to hold the third set of one or more electrodes against the subject'"'"'s body on a first side of the target region, at a position that is longitudinally between the first set of one or more electrodes and the second set of one or more electrodes;
a fourth set of one or more capacitively coupled electrodes; and
a fourth substrate configured to hold the fourth set of one or more electrodes against the subject'"'"'s body on a second side of the target region that is opposite to the first side, at a position that is longitudinally between the first set of one or more electrodes and the second set of one or more electrodes.
10 Assignments
0 Petitions
Accused Products
Abstract
Tumors in portions of a subject'"'"'s body that have a longitudinal axis (e.g., the torso, head, and arm) can be treated with TTFields by affixing first and second sets of electrodes at respective positions that are longitudinally prior to and subsequent to a target region. An AC voltage with a frequency of 100-500 kHz is applied between these sets of electrodes. This imposes an AC electric field with field lines that run through the target region longitudinally. The field strength is at least 1 V/cm in at least a portion of the target region. In some embodiments, this approach is combined with the application of AC electric fields through the target region in a lateral direction (e.g., front to back and/or side to side) in order to apply AC electric fields with different orientations to the target region.
10 Citations
24 Claims
-
1. An apparatus for treating a target region in a subject'"'"'s body with TTFields, the target region being located in a portion of the subject'"'"'s body that has a longitudinal axis, the apparatus comprising:
-
a first set of one or more capacitively coupled electrodes; a first substrate configured to hold the first set of one or more electrodes against the subject'"'"'s body so that the first set of one or more electrodes surrounds a first part of the subject'"'"'s body at a position that is longitudinally prior to the target region; a second set of one or more capacitively coupled electrodes; a second substrate configured to hold the second set of one or more electrodes against the subject'"'"'s body so that the second set of one or more electrodes surrounds a second part of the subject'"'"'s body at a position that is longitudinally subsequent to the target region; a third set of one or more capacitively coupled electrodes; a third substrate configured to hold the third set of one or more electrodes against the subject'"'"'s body on a first side of the target region, at a position that is longitudinally between the first set of one or more electrodes and the second set of one or more electrodes; a fourth set of one or more capacitively coupled electrodes; and a fourth substrate configured to hold the fourth set of one or more electrodes against the subject'"'"'s body on a second side of the target region that is opposite to the first side, at a position that is longitudinally between the first set of one or more electrodes and the second set of one or more electrodes. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
-
-
12. A method of treating a target region in a subject'"'"'s body with TTFields, the target region being located in a portion of the subject'"'"'s body that has a longitudinal axis, the method comprising:
-
affixing a first set of one or more electrodes to the subject'"'"'s body so as to surround a first part of the subject'"'"'s body at a position that is longitudinally prior to the target region; affixing a second set of one or more electrodes to the subject'"'"'s body so as to surround a second part of the subject'"'"'s body at a position that is longitudinally subsequent to the target region; and applying a first AC voltage with a frequency of 100-500 kHz between the first set of one or more electrodes and the second set of one or more electrodes so as to impose a first AC electric field with field lines that run through the target region longitudinally, the first AC electric field having a field strength of at least 1 V/cm in at least a portion of the target region. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
-
Specification