TREATMENT OF BLEEDING BY NON-INVASIVE STIMULATION
First Claim
1. A method of reducing bleed time in a subject, the method comprising:
- non-invasively stimulating a subject'"'"'s vagus nerve with an external mechanical actuator in a manner that activates the cholinergic anti-inflammatory pathway and reduces bleed time by at least 20%.
4 Assignments
0 Petitions
Accused Products
Abstract
Devices, systems and methods for stimulating (e.g., noninvasively) a subject'"'"'s inflammatory reflex are provided to reduce bleed time. The method may include the step of non-invasively stimulating the inflammatory reflex (e.g., the vagus nerve, the splenic nerve, the hepatic nerve, the facial nerve, and the trigeminal nerve) of a subject, such as by mechanical stimulation, in a manner which significantly reduces bleed time in the subject. Devices for non-invasively stimulating the inflammatory reflex may include a movable tip or actuator that is controlled to mechanically stimulate the ear. The devices may be hand-held or wearable, and may stimulate the cymba conchae region of the subject'"'"'s ear.
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Citations
20 Claims
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1. A method of reducing bleed time in a subject, the method comprising:
non-invasively stimulating a subject'"'"'s vagus nerve with an external mechanical actuator in a manner that activates the cholinergic anti-inflammatory pathway and reduces bleed time by at least 20%. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A method of reducing bleed time in a subject, the method comprising:
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providing a mechanical actuator; and non-invasively stimulating with the mechanical actuator the subject'"'"'s ear to stimulate an inflammatory reflex in a manner that activates the cholinergic anti-inflammatory pathway and reduces bleed time in the subject by at least 20%. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A method of reducing bleed time in a subject, the method comprising:
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providing a mechanical actuator, wherein the mechanical actuator is wearable on the subject'"'"'s ear and comprises a magnetic driver adapted to be located on one side of the ear and a magnetic element adapted to be located on the opposing side of the ear; and non-invasively mechanically stimulating with the mechanical actuator a subject'"'"'s ear to stimulate an inflammatory reflex in a manner that activates the cholinergic anti-inflammatory pathway and reduces bleed time by at least 20 percent in the subject.
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Specification