OPTICAL COHERENCE TOMOGRAPHIC DEVICE

• US 20180035894A1
• Filed: 08/04/2017
• Published: 02/08/2018
• Est. Priority Date: 08/05/2016
• Status: Active Grant

• Current Assignee: Tomey Corporation
• Original Assignee: Tomey Corporation
• Inventors: Yamanari, Masahiro
• Granted Patent: US 10,918,285 B2
• Time in Patent Office: Days
• CPC Class Codes: A61B 3/102 for optical coherence tomography [OCT]
• CPC Class Codes: A61B 5/0066 Optical coherence imaging
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: G01B 9/02027 Two or more interferometric channels or interferometers
• CPC Class Codes: G01B 9/02041 characterised by particular imaging or detection techniques
• CPC Class Codes: G01B 9/02055 Reduction or prevention of errors; Testing; Calibration
• CPC Class Codes: G01B 9/02083 characterised by particular signal processing and presentation
• CPC Class Codes: G01B 9/02091 Tomographic interferometers, e.g. based on optical coherence

Abstract

An optical coherence tomographic device configured to acquire a tomographic image of a subject by using an optical interferometry is provided. The optical coherence tomographic device include: a detector configured to detect interference light acquired by the optical interferometry, and to output an interference signal of the interference light; and a processor configured to calculate von Neumann entropy of noise components by using the noise components and signal intensities of the interference signals corresponding to at least one interference light detected by the detector.

Claims

1. An optical coherence tomographic device configured to acquire a tomographic image of a subject by using an optical interferometry, the optical coherence tomographic device comprising:

a detector configured to detect interference light acquired by the optical interferometry, and to output an interference signal of the interference light; and

a processor configured to calculate von Neumann entropy of noise components by using the noise components and signal intensities of the interference signals corresponding to at least one interference light detected by the detector.

2. The optical coherence tomographic device of claim 1, wherein the processor is further configured to:

calculate von Neumann entropy of the interference signal; and

to calculate von Neumann entropy that indicates a polarization property of the subject by removing the von Neumann entropy of noise components from the calculated von Neumann entropy of the interference signal.

3. The optical coherence tomographic device of claim 2, wherein the von Neumann entropy of noise components is calculated based on a polarization property accumulated along a depth direction of the subject.

4. The optical coherence tomographic device of claim 3, wherein the polarization property accumulated along the depth direction of the subject is characterized by at least one of Jones matrix, Mueller matrix, Jones vector and Stokes vector.

5. The optical coherence tomographic device of claim 2, wherein the von Neumann entropy of noise components is calculated based on a polarization property localized along a depth direction of the subject.

6. The optical coherence tomographic device of claim 5, wherein the polarization property localized along the depth direction of the subject is characterized by at least one of Jones matrix, Mueller matrix, Jones vector and Stokes vector.

7. The optical coherence tomographic device of claim 1, wherein the detector is configured to;

divide the interference light into at least two different polarization components; and

to detect each of the polarization components of the interference light.

8. An optical coherence tomographic device configured to acquire a tomographic image of a subject by using an optical interferometry, the optical coherence tomographic device comprising:

a detector configured to detect interference light acquired by the optical interferometry, and to output an interference signal of the interference light; and

a processor configured to calculate covariance matrix that indicates a polarization property of the subject based on the interference signal outputted by the detector, and to calculate von Neumann entropy based on the calculated covariance matrix,

wherein the processor is configured to, when a number of samples of an ensemble average of the covariance matrix to be used for calculation is insufficient, correct an eigenvalues of the ensemble averaged covariance matrix, and calculate the von Neumann entropy by using the corrected eigenvalues.

9. An optical coherence tomographic device configured to acquire a tomographic image of a subject by using an optical interferometry, the optical coherence tomographic device comprising:

a detector configured to detect interference light acquired by the optical interferometry, and to output an interference signal of the interference light; and

a processor configured;

to measure Jones matrices that indicate a polarization property of the subject based on the interference signal outputted by the detector;

perform a moving average process relative to the measured Jones matrices;

perform the moving average process relative to covariance matrices of Jones matrices that has been subjected to the moving average process; and

estimate the Jones matrix by using eigenvalue decomposition; and

calculate von Neumann entropy by using the eigenvalue decomposition.

10. The optical coherence tomographic device of claim 9, further comprising a scanner configured to scan measurement light,

wherein the scanner is configured to scan the subject with the measurement light such that three-dimensional volume data of the subject is acquired for acquiring the measured Jones matrices.

11. The optical coherence tomographic device of claim 9, further comprising a scanner configured to scan measurement light,

wherein the scanner is configured to scan a predefined region of the subject with the measurement light at least two times for acquiring the measured Jones matrices.

12. The optical coherence tomographic device of claim 9, further comprising a scanner configured to scan measurement light,

wherein the scanner is configured to scan the three-dimensional regions of the subject with the measurement light at least two times for acquiring the measured Jones matrices.

13. The optical coherence tomographic device of claim 9, wherein the processor is configured to:

set a threshold value based on a signal intensity of the measured Jones matrices; and

perform the moving average process of the measured Jones matrices by using only pixels that have a signal intensity equal to or greater than the threshold value.

14. The optical coherence tomographic device of claim 9, wherein the processor is configured to set a threshold value based on a signal intensity of raw data of the measured Jones matrices, and perform the moving average process of the covariance matrix by using only pixels that have a signal intensity equal to or larger than the threshold value.

15. The optical coherence tomographic device of claim 9, wherein the processor is configured to:

set a threshold value based on a signal intensity of raw data of the measured Jones matrices; and

output an image in which pixels that have a signal intensity equal to or smaller than the threshold value are masked in an arbitrary color.