MOBILE APPLICATION TO PROMPT PHYSICAL ACTION TO MEASURE PHYSIOLOGIC RESPONSE IN IMPLANTABLE DEVICE

• US 20180035956A1
• Filed: 05/30/2017
• Published: 02/08/2018
• Est. Priority Date: 08/02/2016
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: GUNDERSON, Bruce D., WARMAN, Eduardo N.
• Granted Patent: US 10,952,686 B2
• Time in Patent Office: Days
• CPC Class Codes: A61B 2560/0209 adapted for power saving
• CPC Class Codes: A61B 2560/0462 Apparatus with built-in sensors
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/0538 invasively, e.g. using a catheter
• CPC Class Codes: A61B 5/0809 by impedance pneumography
• CPC Class Codes: A61B 5/1116 Determining posture transitions
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/686 Permanently implanted devices, e.g. pacemakers, other stimulators, biochips A61B5/6861 takes precedence
• CPC Class Codes: A61B 5/6882 Anchoring means
• CPC Class Codes: A61B 5/747 in case of emergency, i.e. alerting emergency services
• CPC Class Codes: A61N 1/08 Arrangements or circuits for monitoring, protecting, controlling or indicating for external stimulators A61N1/3603; for implantable neurostimulators A61N1/36128; for heart stimulators A61N1/37; for defibrillators A61N1/3925
• CPC Class Codes: A61N 1/36 for stimulation
• CPC Class Codes: A61N 1/37282 characterised by communication with experts in remote locations using a network
• CPC Class Codes: G08B 1/08 using electric transmission ; transformation of alarm signals to electrical signals from a different medium, e.g. transmission of an electric alarm signal upon detection of an audible alarm signal
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 80/00 ICT specially adapted for facilitating communication between medical practitioners or patients, e.g. for collaborative diagnosis, therapy or health monitoring

Abstract

A user equipment that includes a touchscreen, and at least one processor configured to generate first timestamp data based upon detection of a first touch event on the touchscreen, and second timestamp data based upon detection of a second touch event on the touchscreen, for calculation by a medical device system of a patient-specific functional status parameter associated with a Sit-To-Stand performance test over a time segment inclusively bounded by a first time defined by the first timestamp data and a second time defined by the second timestamp data.

Claims

1. An implantable medical device (IMD) comprising:

communication circuitry configured to establish a communication link and transfer data between the IMD intra-corpus and a computing device extra-corpus;

accelerometer circuitry configured to generate a plurality of signals including a sagittal axis signal, a vertical axis signal and a transverse axis signal; and

processing circuitry configured to;

acquire first timestamp data and second timestamp data each one generated by the computing device and received by the IMD via the communication circuitry;

calculate a patient-specific functional status parameter associated with a Sit-To-Stand test from at least one of the sagittal axis signal, the vertical axis signal and the transverse axis signal over a time segment inclusively bounded by a first time defined by the first timestamp data and a second time defined by the second timestamp data; and

in response to a command, activate the communication circuitry to transmit the patient-specific functional status parameter from the IMD to the computing device.

2. The device of claim 1, wherein the processing circuitry is configured to:

calculate rate of change of a segment of at least one of the sagittal axis signal, the vertical axis signal and the transverse axis signal within the time segment; and

calculate the patient-specific functional status parameter based on the calculated rate of change.

3. The device of claim 6, wherein the processing circuitry is configured to:

calculate a definite integral over a segment of at least one of the sagittal axis signal, the vertical axis signal and the transverse axis signal within the time segment; and

calculate the patient-specific functional status parameter based on the calculated definite integral.

4. The device of claim 6, wherein the processing circuitry is configured to:

calculate a length of time of a segment of at least one of the sagittal axis signal, the vertical axis signal and the transverse axis signal within the time segment; and

calculate the patient-specific functional status parameter based on the calculated length of time.

5. The device of claim 1, wherein the processing circuitry is configured to:

calculate a peak amplitude of a segment of at least one of the sagittal axis signal, the vertical axis signal and the transverse axis signal within the time segment; and

calculate the patient-specific functional status parameter based on the calculated peak amplitude.

6. The device of claim 1, wherein the processing circuitry is configured to:

calculate a peak-peak amplitude of a segment of at least one of the sagittal axis signal, the vertical axis signal and the transverse axis signal within the time segment; and

calculate the patient-specific functional status parameter based on the calculated peak-peak amplitude.

7. The device of claim 1, wherein the processing circuitry is configured to:

calculate at least one baseline characteristic from the at least one of the sagittal axis signal, the vertical axis signal and the transverse axis signal, wherein the at least one baseline characteristic is associated with a movement-free sitting position posture; and

calculate the patient-specific functional status parameter based on the at least one baseline characteristic.

8. The device of claim 1, wherein the processing circuitry is configured to:

calculate the patient-specific functional status parameter from at least one characteristic of at least one of the sagittal axis signal, the vertical axis signal and the transverse axis signal over multiple distinct time intervals;

calculate an averaged patient-specific functional status parameter from each interval-specific calculated patient-specific functional status parameter; and

activate the communication circuitry to transmit the averaged patient-specific functional status parameter from the IMD to the computing device.

9. The device of claim 1, wherein the processing circuitry is configured to:

calculate a time occurrence of at least one inflection point of at least one of the sagittal axis signal, the vertical axis signal and the transverse axis signal within the time segment; and

calculate the patient-specific functional status parameter based on the calculated time occurrence.

10. The device of claim 1, wherein the processing circuitry is configured to:

in response to an activation command, power-on the accelerometer circuitry to generate the plurality of signals including the sagittal axis signal, the vertical axis signal and the transverse axis signal.

11. The device of claim 1, wherein the processing circuitry is configured to:

in response to a deactivation command, power-down the accelerometer circuitry for a predetermined period of time to conserve power of the IMD.

12. The device of claim 1, wherein the processing circuitry is configured to:

calculate a symmetry characteristic metric from at least one segment of the at least one of the sagittal axis signal, the vertical axis signal and the transverse axis signal within the time segment, wherein the at least one segment is associated with a Sit-To-Stand or stand-to-sit movement of the Sit-To-Stand test; and

calculate the patient-specific functional status parameter based on the calculated symmetry characteristic metric.

13. The device of claim 12, wherein the processing circuitry is configured to:

calculate a velocity metric from the at least one of the sagittal axis signal, the vertical axis signal and the transverse axis signal within the time segment to determine an average or instantaneous velocity associated with a Sit-To-Stand or stand-to-sit movement of the Sit-To-Stand test; and

calculate the patient-specific functional status parameter based on the calculated velocity metric.

14. The device of claim 12, wherein the processing circuitry is configured to:

calculate a distance metric from the at least one of the sagittal axis signal, the vertical axis signal and the transverse axis signal within the time segment to determine a total or intermediate displacement associated with a Sit-To-Stand or stand-to-sit movement of the Sit-To-Stand test; and

calculate the patient-specific functional status parameter based on the calculated distance metric.

15. The device of claim 12, wherein the processing circuitry is configured to:

calculate a kinetic energy metric from the at least one of the sagittal axis signal, the vertical axis signal and the transverse axis signal within the time segment to determine a total or intermediate energy expenditure associated with a Sit-To-Stand or stand-to-sit movement of the Sit-To-Stand test; and

calculate the patient-specific functional status parameter based on the calculated kinetic energy metric.

16. The device of claim 15, wherein the processing circuitry is configured to:

calculate a potential energy metric from the at least one of the sagittal axis signal, the vertical axis signal and the transverse axis signal within the time segment and the distance metric to determine a total or intermediate increase or decrease in potential energy associated with a Sit-To-Stand or stand-to-sit movement of the Sit-To-Stand test; and

calculate the patient-specific functional status parameter based on the calculated potential energy metric.

17. The device of claim 12, wherein the processing circuitry is configured to:

calculate a derivative metric from a segment of the at least one of the sagittal axis signal, the vertical axis signal and the transverse axis signal within the time segment to determine erratic movement associated with a Sit-To-Stand or stand-to-sit movement of the Sit-To-Stand test; and

calculate the patient-specific functional status parameter based on the calculated derivative metric.

18. A method comprising:

by an implantable medical device, intra-corpus,

generating a plurality of signals including a sagittal axis signal, a vertical axis signal and a transverse axis signal;

receiving, from a computing device extra-corpus, first timestamp data and second timestamp data each one generated by the computing device and received by the implantable medical device over a communication link;

calculating a patient-specific functional status parameter associated with a Sit-To-Stand test from at least one of the sagittal axis signal, the vertical axis signal and the transverse axis signal over a time segment inclusively bounded by a first time defined by the first timestamp data and a second time defined by the second timestamp data; and

in response to a command, transmitting the patient-specific functional status parameter to the computing device.

19. The method of claim 18, further comprising:

calculating rate of change of a segment of at least one of the sagittal axis signal, the vertical axis signal and the transverse axis signal within the time segment; and

calculating the patient-specific functional status parameter based on the calculated rate of change.

20. The method of claim 18, further comprising:

calculating a definite integral over a segment of at least one of the sagittal axis signal, the vertical axis signal and the transverse axis signal within the time segment; and

calculating the patient-specific functional status parameter based on the calculated definite integral.