DEVICES AND METHODS FOR GLAUCOMA TREATMENT
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Abstract
Intraocular stents and applicators are disclosed for treating glaucoma. The stents are configured to extend between the anterior chamber of the eye and Schlemm'"'"'s canal for enhancing outflow of aqueous from the anterior chamber so as to reduce intraocular pressure. The stents can have features for anchoring the stent into Schlemm'"'"'s canal as well as preventing the walls of Schlemm'"'"'s canal from closing the outlet of the stents. The applicators can be steerable so as to make implantation easier. Additionally, the applicators can be configured to hold a plurality of stents so that multiple stents can be implanted through one incision without removing the applicator from the incision between serial implantations.
13 Citations
79 Claims
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1-42. -42. (canceled)
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43. An instrument for delivering implants for treating an ophthalmic condition and dispensing implants through a wall of a physiologic outflow pathway, the instrument comprising:
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an injection sheath defining a lumen and comprising a distal stent-holding section, the distal stent-holding section sized to be introduced into an eye through an incision in the eye; a plurality of implants positioned in the lumen, each of said implants comprising a proximal head, a distal tapered base portion, and an intermediate waist portion disposed between the head and the base portion, the waist portion being substantially cylindrical and having an outer dimension that is smaller than an outer dimension of a distal end of the head and smaller than an outer dimension of a proximal end of the base portion, wherein the outer dimension of the base portion tapers in a direction longitudinally away from the waist portion; and a trocar extending through each of the plurality of implants, wherein a distal tip of said trocar is sufficiently sharp to cut through said wall of said physiologic outflow pathway. - View Dependent Claims (44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54)
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55. An instrument for delivering implants for treating an ophthalmic condition and dispensing implants through a wall of a physiologic outflow pathway, the instrument comprising:
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an insertion sheath defining a lumen, a distal portion of the insertion sheath sized to be introduced into an eye through an incision in the eye; a trocar disposed in said lumen, said trocar comprising a distal tip having a cutting end sufficiently sharp to cut through said wall of said physiologic outflow pathway; and a plurality of biocompatible implants positioned in the lumen and mounted on the trocar, each of said implants comprising a head, a base portion, and a waist portion disposed between the head and the base portion, wherein an outer dimension of the waist portion is smaller than an outer dimension of an immediately-adjacent portion of the head and smaller than an outer dimension of an immediately-adjacent portion of the base portion, each of the plurality of implants being mounted on the trocar such that the outer dimension of the base portion tapers toward the distal tip of the trocar. - View Dependent Claims (56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66)
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67. An instrument for delivering implants for treating an ophthalmic condition and dispensing implants through a wall of a physiologic outflow pathway, the instrument comprising:
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an injection sheath defining a lumen, a distal portion of said injection sheath sized to be introduced into an anterior chamber of an eye; a trocar disposed in said lumen, said trocar comprising a distal tip being sufficiently sharp to cut through said wall of said physiologic outflow pathway; and a plurality of implants mounted on the trocar and positioned in the distal portion of the injection sheath, each of said implants comprising a tapered base portion having an outer surface that tapers toward the distal tip of the trocar, each of said implants further comprising a waist portion that extends proximally away from a proximal end of the base portion, an outer dimension of the waist portion being smaller than an outer dimension of the proximal end of the base portion, each of said implants further comprising a head portion that extends proximally away from a proximal end of the waist portion, an outer dimension of the waist portion being smaller than an outer dimension of the distal end of the head portion. - View Dependent Claims (68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79)
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Specification