APPARATUS FOR AND METHOD OF PROCESSING BIOLOGICAL SAMPLES
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Abstract
The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing. Other embodiments include automated systems, automated devices, automated cartridges and automated methods for separation, preparation and purification of nucleic acids, such as DNA or RNA or fragments thereof, including plasmid DNA, genomic DNA, bacterial DNA, viral DNA and any other DNA, and for automated systems, automated devices, automated cartridges and automated methods for processing, separation and purification of proteins, peptides and the like.
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Citations
42 Claims
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1-30. -30. (canceled)
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31. A bioprocessing cartridge comprising:
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a first bioprocessing chamber, wherein the first bioprocessing chamber includes a first solid support, and wherein the first solid support is configured to filter debris from cell lysate; a second bioprocessing chamber, wherein the second bioprocessing chamber includes a second solid support, and wherein the second solid support is configured to reversibly bind nucleic acids; a plurality of fluid channels in fluid communication with the first and second bioprocessing chambers; and one or more reagent reservoirs, wherein the one or more reagent reservoirs are in fluid communication with one or more of the first and second bioprocessing chambers. - View Dependent Claims (32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42)
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Specification