DEVICES AND METHODS FOR MONITORING PHYSIOLOGIC PARAMETERS

• US 20180140252A1
• Filed: 01/05/2018
• Published: 05/24/2018
• Est. Priority Date: 11/16/2015
• Status: Active Grant

• Current Assignee: Respirix, Inc.
• Original Assignee: Respirix, Inc.
• Inventors: LUXON, Evan S., BURNETT, Daniel R., VERGARA, Alexander, ZIEGLER, Mark, VISWANATHAN, Nikhil, HEMATI, Michael
• Granted Patent: US 11,707,227 B2
• Time in Patent Office: Days
• CPC Class Codes: A61B 2562/0247 Pressure sensors
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/0245 by using sensing means generating electric signals, i.e. ECG signals
• CPC Class Codes: A61B 5/03 Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs A61B5/205 takes precedence
• CPC Class Codes: A61B 5/0803 Recording apparatus specially adapted therefor
• CPC Class Codes: A61B 5/087 Measuring breath flow
• CPC Class Codes: A61B 5/097 Devices for facilitating collection of breath or for directing breath into or through measuring devices
• CPC Class Codes: A61B 5/14507 specially adapted for measuring characteristics of body fluids other than blood devices for taking samples of body liquids A61B10/0045
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61B 5/4884 inducing physiological or psychological stress, e.g. applications for stress testing
• CPC Class Codes: A61B 5/682 Mouth, e.g., oral cavity; tongue; Lips; Teeth
• CPC Class Codes: A61B 5/6826 Finger
• CPC Class Codes: A61M 16/00 Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes stimulating the respiratory movement by mechanical, pneumatic or electrical means, iron lungs combined with gas breathing means A61H31/00
• CPC Class Codes: A61M 16/06 Respiratory or anaesthetic masks
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2230/04 : Heartbeat characteristics, e.g. ECG, blood pressure modulation
• CPC Class Codes: A61M 2230/40 : Respiratory characteristics
• CPC Class Codes: G09B 19/003 : Repetitive work cycles; Sequence of movements

Abstract

Devices and methods for monitoring physiologic parameters are described where an airway device, in one embodiment, may comprise a mouthpiece section and an opening section defining one or more airway lumens therethrough with a first sensor in fluid communication with the one or more airway lumens and a second sensor positioned upon a hand-piece for contact against a portion of the user. The first sensor may be configured to detect an airway pressure when a user inhales or exhales through the one or more airway lumens, and the second sensor may be configured to detect a physiological signal from the user. Additionally, a controller may be in communication with the first and second sensors where the controller is programmed to correlate pressure oscillations in the airway pressure with heartbeats.

Claims

1. An airway device, comprising:

a mouthpiece section and an opening section defining one or more airway lumens therethrough;

a first sensor in fluid communication with the one or more airway lumens and configured to detect an airway pressure when a user inhales or exhales through the one or more airway lumens;

a second sensor positioned upon a hand-piece for contact against a portion of the user and configured to detect a physiological signal from the user; and

a controller in communication with the first and second sensors, wherein the controller is programmed to correlate pressure oscillations in the airway pressure received from the first sensor with heartbeats received from the first sensor, the second sensor, or pressure data corresponding to a rough airway pressure, and wherein the controller is further programmed to gate the pressure oscillations in the airway pressure to a timing of the heartbeats.

2. The device of claim 1 wherein the second sensor comprises an electrocardiogram sensor.

3. The device of claim 2 wherein the first sensor is configured to detect cardiogenic oscillations in the airway pressure.

4. The device of claim 3 wherein the controller is programmed to correlate the pressure oscillations within the airway pressure with a systolic pulse data or a diastolic pulse data detected from the physiological signal

5. The device of claim 3 wherein the controller is programmed to correlate the pressure oscillations within the airway pressure with a QRS complex detected from the physiological signal.

6. The device of claim 1 wherein the second sensor comprises a pulse oximeter or photoplethysmograph sensor.

7. The device of claim 1 wherein the second sensor is positioned upon a surface of the hand-piece such that the second sensor contacts a hand or finger of the user.

9. The device of claim 1 wherein the controller is further programmed to sense the airway pressure during exhalation from the user and to determine whether the airway pressure is within a predetermined range.

10. The device of claim 1 wherein the controller is further programmed to detect a resulting exhalation from the user.

12. The device of claim 10 wherein the controller is programmed to indicate to the user whether the resulting exhalation is within a predetermined pressure range.

16. The device of claim 10 wherein the controller is further programmed to provide a feedback to the user relating to parameters of the resulting exhalation.

17. The device of claim 1 further comprising a server located remotely from the device, wherein the device is communication with the server.

18. The device of claim 1 wherein the controller is further programmed to provide a prompt to the user to change a physical position of the user.

19. The device of claim 18 wherein the physical position comprises a supine or sitting position.

22. The device of claim 1 further comprising a restrictor which restricts airflow through the one or more airway lumens.

23. The device of claim 1 wherein the controller comprises a smartphone in communication with the first and second sensors.

25. The device of claim 1 further comprising a third sensor in fluid communication with the one or more airway lumens and configured to detect the rough airway pressure through the one or more airway lumens.

8. (canceled)

11. (canceled)

13-15. -15. (canceled)

20-21. -21. (canceled)

24. (canceled)

26. A method of correlating physiologic parameters, comprising:

detecting via a first sensor an airway pressure of a user while inhaling or exhaling through one or more airway lumens of a respiration device having a mouthpiece section and an opening section;

detecting via a second sensor positioned upon a hand-piece of the respiration device a physiological signal sensed from the user in contact with the second sensor;

correlating via a controller pressure oscillations in the airway pressure received from the first sensor with a timing of heartbeats received from the first sensor, the second sensor, or pressure data corresponding to a rough airway pressure; and

gating the pressure oscillations in the airway pressure to the timing of heartbeats.

27. The method of claim 26 wherein detecting via a first sensor comprises detecting cardiogenic oscillations in the airway pressure.

28. The method of claim 27 wherein correlating via a controller comprises correlating the pressure oscillations with a timing of a systolic pulse data or a diastolic pulse data detected from the physiological signal.

29. The method of claim 27 wherein correlating via a controller comprises correlating the pressure oscillations with a timing of a QRS complex detected from the physiological signal.

30. The method of claim 26 wherein detecting via a second sensor comprises detecting via a pulse oximeter or photoplethysmograph.

31. The method of claim 26 wherein detecting via a second sensor comprises detecting the electrical signal through a hand or finger of the user in contact with the second sensor.

33. The method of claim 26 wherein detecting via a first sensor comprises detecting an exhalation from the user and determining whether the airway pressure is within a predetermined range.

40. The method of claim 26 further comprising transmitting information from the respiration device to a server located remotely from the respiration device.

41. The method of claim 26 further comprising prompting the user to change a physical position of the user.

42. The method of claim 26 wherein the physical position comprises a supine or sitting position.

43. The method of claim 26 further comprising restricting airflow through the one or more airway lumens of the respiration device prior to correlating via a controller.

44. The method of claim 26 further comprising transmitting information between the respiration device and a smartphone in communication with the first and second sensors.

46. The method of claim 26 further comprising detecting via a third sensor in fluid communication with the one or more airway lumens the rough airway pressure through the one or more airway lumens.

32. (canceled)

34-39. -39. (canceled)

45. (canceled)