METHODS AND DEVICES FOR STIMULATING CELL PROLIFERATION
First Claim
1. A method for increasing periodontal cell proliferation, the method comprising:
- providing a vibrational dental device configured to vibrate at a frequency higher than about 60 Hz, wherein a peak acceleration magnitude generated by the vibrational dental device in the horizontal direction is substantially greater than that in the vertical direction;
mechanically stimulating, using the vibrational dental device, periodontal cells, including at least one of human osteoblasts and fibroblasts, for a treatment period of less than about 10 minutes daily; and
wherein the number of the periodontal cells at the end of the period of time is increased.
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Abstract
Embodiments of the present disclosure are directed to devices and methods for stimulating cell proliferation. In one implementation, a method for increasing cell proliferation is provided. The method includes providing a vibrational dental device configured to vibrate at a frequency higher than about 60 Hz. The method also includes mechanically stimulating, using the vibrational dental device, cells for a treatment period of less than about 10 to 20 minutes daily. The method may further include generating a peak acceleration magnitude in the horizontal direction substantially greater than that in the vertical direction. The number of the cells at the end of the period of time is increased. The cells may include at least one of human osteoblasts and fibroblasts.
3 Citations
23 Claims
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1. A method for increasing periodontal cell proliferation, the method comprising:
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providing a vibrational dental device configured to vibrate at a frequency higher than about 60 Hz, wherein a peak acceleration magnitude generated by the vibrational dental device in the horizontal direction is substantially greater than that in the vertical direction; mechanically stimulating, using the vibrational dental device, periodontal cells, including at least one of human osteoblasts and fibroblasts, for a treatment period of less than about 10 minutes daily; and wherein the number of the periodontal cells at the end of the period of time is increased. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 22)
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19. A method for accelerating orthodontic tooth movement, the method comprising:
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providing a mouthpiece of a vibrational dental device to be clamped by the user'"'"'s teeth; and mechanically stimulating, using the vibrational dental device, cells of the user, including at least one of osteoblasts in alveolar bone and periodontal ligament fibroblasts, for a treatment period of less than about 10 minutes daily at a frequency higher than about 60 Hz, wherein a peak acceleration magnitude of the mouthpiece in the horizontal direction is substantially greater than that in the vertical direction. - View Dependent Claims (20, 21)
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23. A dental device for increasing cell proliferation, the dental device comprising means for
mechanically stimulating cells, including at least one of human osteoblasts and periodontal ligament fibroblasts, at a frequency higher than about 60 Hz for a treatment period of less than about 10 minutes daily, wherein a peak acceleration magnitude generated by the vibrational dental device in the horizontal direction is substantially greater than that in the vertical direction.
Specification