ANALYTE SENSOR

• US 20180160949A1
• Filed: 02/07/2018
• Published: 06/14/2018
• Est. Priority Date: 02/22/2006
• Status: Abandoned Application

• Current Assignee: DexCom Incorporated
• Original Assignee: DexCom Incorporated
• Inventors: Brister, Mark, Neale, Paul V., Brauker, James H., Thrower, James Patrick, Goode, JR., Paul V.
• Application Number:
  US15/891,201
• Publication Number:
  US 20180160949A1
• Time in Patent Office: Days
• CPC Class Codes: A61B 5/0004 characterised by the type of physiological signal transmitted
• CPC Class Codes: A61B 5/002 Monitoring the patient using a local or closed circuit, e.g. in a room or building A61B5/0017 takes precedence
• CPC Class Codes: A61B 5/1411 by percutaneous method, e.g. by lancet
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/15142 Devices intended for single use, i.e. disposable
• CPC Class Codes: A61B 5/72 Signal processing specially adapted for physiological signals or for diagnostic purposes character recognition, recognising digital ink, document-oriented image-based pattern recognition G06V30/00; recognition or understanding of postal images G06V30/424
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: A61B 5/746 Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms alarms per se G08B

Abstract

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Claims

1-18. -18. (canceled)

19. A method for monitoring glucose concentration in a biological sample of a host, the method comprising:

producing a data stream indicative of a glucose concentration of a host using a continuous glucose sensor, wherein at least a portion of the continuous glucose sensor is configured for transcutaneous insertion through a skin of the host;

applying sensor data associated with the data stream to a prospectively-generated conversion function to prospectively convert, using a first processor, the sensor data to generate real-time calibrated glucose concentration information;

triggering a first alert responsive to the real-time calibrated glucose concentration information;

applying the sensor data to a retrospectively-generated conversion function to retrospectively convert, using a second processor, the sensor data associated with the data stream to generate historical calibrated glucose concentration information;

triggering a second alert responsive to the historical calibrated glucose concentration information; and

selectively displaying a graphical representation of the real-time calibrated glucose concentration or the historical calibrated glucose concentration information on a display device.

20. The method of claim 19, wherein the continuous glucose sensor comprises a sensing region and a sensing membrane located over the sensing region.

21. The method of claim 19, further comprising wirelessly transmitting and receiving data between a first device and the display device.

22. The method of claim 21, wherein the first processor is incorporated in the first or the display device.

23. The method of claim 19, wherein the display device is configured to establish a communication link with a first device responsive to a user initiation.

24. The method of claim 19, wherein the second processor is incorporated in the first or the display device.

25. The method of claim 24, wherein the first device is an on-skin device and the display device is a hand-held receiver.

26. The method of claim 25, wherein the hand-held receiver is a cell phone.

27. The method of claim 19, wherein the display device is configured to transmit a request to a first device, and wherein the first device is configured to transmit the sensor data to the display device in response to the first device receiving the request.

28. The method of claim 19, further comprising downloading software, wherein the software comprises computer-readable instructions that, when executed by the first or the second processor, perform the retrospective conversion and the displaying.

29. The method of claim 19, wherein the retrospectively-generated conversion function is based on a change in sensitivity of the continuous glucose sensor not accounted for in the prospectively-generated conversion function.