ASSAYS FOR TIMP2 HAVING IMPROVED PERFORMANCE IN BIOLOGICAL SAMPLES
First Claim
Patent Images
1. An isolated rabbit monoclonal antibody which specifically binds human TIMP-2, wherein the monoclonal antibody binds with an affinity of at least 108 M−
- 1 to a polypeptide, wherein the sequence of said polypeptide consists of a sequence selected from the group consisting of;
1 Assignment
0 Petitions
Accused Products
Abstract
The invention provides TIMP2 immunoassays with improved clinical performance, particularly when used in the evaluation of renal injuries. The immunoassays rely on the selection and use of antibodies and antibody pairs that exhibit improved assay performance when used in complex clinical specimens such as biological fluids, and particularly when used in rapid assay formats such as lateral flow test devices.
-
Citations
12 Claims
-
1. An isolated rabbit monoclonal antibody which specifically binds human TIMP-2, wherein the monoclonal antibody binds with an affinity of at least 108 M−
- 1 to a polypeptide, wherein the sequence of said polypeptide consists of a sequence selected from the group consisting of;
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
- 1 to a polypeptide, wherein the sequence of said polypeptide consists of a sequence selected from the group consisting of;
Specification