DEVICE AND METHOD FOR DETERMINING ANALYTE LEVELS
First Claim
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1. An implantable device for measuring an analyte in a biological fluid, comprising:
- a) a housing comprising an electronic circuit; and
b) a sensor operably connected to said electronic circuit of said housing, said sensor comprising;
i) a member for determining the amount of glucose in a biological sample;
ii) a bioprotective membrane, said bioprotective membrane positioned more distal to said housing than said glucose determining member and substantially impermeable to macrophages; and
iii) an angiogenic layer, said angiogenic layer positioned more distal to said housing than said bioprotective membrane.
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Abstract
Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices include unique architectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.
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Citations
1 Claim
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1. An implantable device for measuring an analyte in a biological fluid, comprising:
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a) a housing comprising an electronic circuit; and b) a sensor operably connected to said electronic circuit of said housing, said sensor comprising; i) a member for determining the amount of glucose in a biological sample; ii) a bioprotective membrane, said bioprotective membrane positioned more distal to said housing than said glucose determining member and substantially impermeable to macrophages; and iii) an angiogenic layer, said angiogenic layer positioned more distal to said housing than said bioprotective membrane.
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Specification