Methods and Compositions for Enhancing Memory and/or Reducing Fear and/or Pain of a Host by Administering a Probiotic

• US 20180200312A1
• Filed: 01/17/2018
• Published: 07/19/2018
• Est. Priority Date: 01/17/2017
• Status: Abandoned Application

• Current Assignee: Battelle Memorial Institute, Regents of the University of California (University of California)
• Original Assignee: Battelle Memorial Institute, Regents of the University of California (University of California)
• Inventors: Snijders, Antoine M., Mao, Jian-Hua, Langley, Sasha A., Metz, Thomas O., Jansson, Janet K.
• Application Number:
  US15/873,823
• Publication Number:
  US 20180200312A1
• Time in Patent Office: Days
• CPC Class Codes: A61K 35/741 Probiotics probiotic yeast, e.g. saccharomyces A61K36/06
• CPC Class Codes: A61K 35/742 Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
• CPC Class Codes: A61K 35/747 Lactobacilli, e.g. L. acidophilus or L. brevis
• CPC Class Codes: A61K 9/0053 Mouth and digestive tract, i.e. intraoral and peroral administration rectal administration A61K9/0031

Abstract

The present invention provides for a probiotic composition designed to enhance memory and/or reduce fear and/or pain of a host, the probiotic composition comprising viable or live cells of one or more of the family/order/strain selected from a group consisting of RF39, Lactobacillaceae, Bacteroidaceae, Lachnospiraceae, Anaeroplasmataceae, Ruminococcaceae, Clostridiales, Clostridiaceae, Rikenellaceae, Erysipelotrichaceae, Peptococcaceae, Turicibacteraceae, Deferribacteraceae, Cytophagaceae, Chitinophagaceae, Coriobacteriaceae, Bifidobacteriaceae, and S24.7. The present invention also provides for a method of enhancing memory and/or reducing fear and/or pain of a host, the method comprising: administering the probiotic composition to a host.

Claims

1. A probiotic composition designed to enhance memory and/or reduce fear and/or pain of a host, the probiotic composition comprising viable or live cells of one or more of the family/order/strain selected from a group consisting of RF39, Lactobacillaceae, Bacteroidaceae, Lachnospiraceae, Anaeroplasmataceae, Ruminococcaceae, Clostridiales, Clostridiaceae, Rikenellaceae, Erysipelotrichaceae, Peptococcaceae, Turicibacteraceae, Deferribacteraceae, Cytophagaceae, Chitinophagaceae, Coriobacteriaceae, Bifidobacteriaceae, and S24.7.

2. The probiotic composition of claim 1 comprising viable or live cells of one or more of the family/order/strain RF39, Lactobacillaceae, Bacteroidaceae, Lachnospiraceae, Anaeroplasmataceae, Ruminococcaceae, Clostridiales, Clostridiaceae, or Rikenellaceae.

3. The probiotic composition of claim 2 comprising viable or live cells of strain RF39 and/or family Lactobacillaceae.

4. The probiotic composition of claim 1 comprising viable or live cells of the family/order/strain RF39, Lactobacillaceae, Bacteroidaceae, Lachnospiraceae, Anaeroplasmataceae, Ruminococcaceae, Clostridiales, Clostridiaceae, and Rikenellaceae.

5. A method of enhancing memory and/or reducing fear and/or pain of a host, the method comprising:

administering a probiotic composition of claim 1 to a host, such that memory is enhanced, and/or fear and/or pain is reduced, for the host.

6. The method of claim 5, wherein the host is a mouse or a human.

7. The method of claim 5, wherein the administrating is an oral administration.