AUTOMATIC OPIOID ANTAGONIST INJECTION SYSTEM

• US 20180200433A1
• Filed: 01/17/2017
• Published: 07/19/2018
• Est. Priority Date: 01/17/2017
• Status: Abandoned Application

• Current Assignee: Denis Baran Cirit
• Original Assignee: Denis Baran Cirit
• Inventors: Cirit, Denis Baran
• Application Number:
  US15/407,634
• Publication Number:
  US 20180200433A1
• Time in Patent Office: Days
• CPC Class Codes: A61K 31/485 Morphinan derivatives, e.g. morphine, codeine
• CPC Class Codes: A61M 2005/14272 for emergency, field or home use, e.g. self-contained kits to be carried by the doctor
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3375 Acoustical, e.g. ultrasonic, measuring means
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2230/005 Parameter used as control input for the apparatus
• CPC Class Codes: A61M 2230/04 Heartbeat characteristics, e.g. ECG, blood pressure modulation
• CPC Class Codes: A61M 2230/42 Rate
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/1454 spring-actuated, e.g. by a clockwork
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00

Abstract

A system for automatically injecting naloxone into a patient, upon detection of physiological parameters indicative of an opioid overdose.

Claims

1. A system for injecting an opioid antagonist into a patient in response to a physiological parameter indicative of an opioid overdose, said system comprising:

a sensor operable to detect, in the patient, a physiological parameter affected by an opioid overdose and generate signals corresponding to said physiological parameter;

a reservoir of an opioid antagonist, and an injector operable to inject opioid antagonist into the patient;

a control system, operably connected to the sensor and the injector, said control system operable to receive the signals corresponding to the physiological parameter and operable to control the injector to inject opioid antagonist into the patient, said control system programmed to determine if the signals corresponding to the physiological parameter are indicative of an opioid overdose, said control system further programmed such that, upon determining that the signals corresponding to the physiological parameter are indicative of an opioid overdose, the control system causes the injector to inject the opioid antagonist into the patient.

2. The system of claim 1, wherein the sensor is a respiration rate sensor, operable to detect the patient'"'"'s respiration rate, and the control system is programmed to determine that a respiration rate below twelve breaths per minute as indicative of an opioid overdose.

3. The system of claim 1, wherein the sensor is a photoplethysmographic sensor operable to detect the patient'"'"'s respiration rate.

4. The system of claim 1, wherein the sensor is ECG sensor operable to detect the patient'"'"'s respiration rate.

5. The system of claim 1, wherein the sensor is a respiration rate sensor, operable to detect the patient'"'"'s respiration rate, and the control system is programmed to determine that a respiration rate below twelve breaths per minute, over a period of at least thirty seconds, as indicative of an opioid overdose.

6. The system of claim 1, wherein the sensor is an acoustic sensor.

7. The system of claim 1, wherein the sensor is a non-contact sensor.

8. The system of claim 1, wherein the sensor is secured to a mounting means configured to hold the sensor proximate to the body of the patient.

9. The system of claim 1, wherein the sensor is secured to a band configured to hold the sensor in contact with a pulse point on the body of the patient.

10. The system of claim 1, wherein the sensor, injector, and control system are disposed within a single housing, and said housing is secured to a mounting structure configured to hold the housing proximate a pulse point on the patient'"'"'s body.

11. The system of claim 1, wherein the sensor and injector are disposed in a single housing, and the controller is disposed in a separate device external to the housing.

12. The system of claim 1, wherein the sensor and injector are disposed in separate housings, and the sensor is secured to a first mounting structure configured to hold the sensor proximate a sensing point on the body of the patient, the injector is secured to a second mounting structure configured to hold the injector proximate an injection site on the body of the patient.

13. The system of claim 1, wherein the sensor is a pulse sensor, operable to detect the patient'"'"'s heart rate, and the control system is programmed to determine that a heart rate below 40 beats per minute as indicative of an opioid overdose.

14. The system of claim 1, wherein the sensor is a photoplethysmographic sensor, operable to detect the patient'"'"'s heart rate.

15. The system of claim 1, wherein the sensor is an ECG sensor, operable to detect the patient'"'"'s heart rate.

16. The system of claim 1, wherein the sensor is a pulse sensor, operable to detect the patient'"'"'s heart rate, and the control system is programmed to determine that a heart rate below 40 beats per minute, over a period of at least thirty seconds, as indicative of an opioid overdose.

17. The system of claim 13, wherein the sensor is secured to a band configured to hold the sensor in contact with a pulse point on the body of the patient.

18. The system of claim 13, wherein the sensor, injector, and control system are disposed within a single housing, and said housing secured to a mounting structure configured to hold the housing proximate a pulse point on the patient'"'"'s body.

19. A method of treating opioid overdose in a patient, said method comprising:

disposing a sensor operable to detect a physiological parameter of the patient affected by an opioid overdose, proximate the body of the patient;

disposing an injector proximate an injection site on the body of the patient, said injector operable to inject an opioid antagonist;

operating a controller to obtain signals corresponding to physiological parameter of the patient, and operating the controller to inject opioid antagonist into the patient when the signals corresponding to physiological parameter of the patient correspond to a physiological parameter indicative of an opioid overdose.

20. The method of claim 19, wherein:

the sensor is a pulse sensor.

21. The method of claim 19, wherein:

the sensor is a respiration rate sensor.

22. The method of claim 19, wherein:

the sensor is a photoplethysmographic sensor.