SYSTEM AND METHOD FOR ADJUSTING INSULIN DELIVERY

• US 20180200435A1
• Filed: 01/12/2018
• Published: 07/19/2018
• Est. Priority Date: 01/13/2017
• Status: Active Grant

• Current Assignee: Insulet Corporation
• Original Assignee: Bigfoot Biomedical, Inc.
• Inventors: Mazlish, Bryan, Desborough, Lane, Naylor, Ross
• Granted Patent: US 10,881,793 B2
• Time in Patent Office: Days
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61K 38/28 Insulins
• CPC Class Codes: A61M 2205/35 Communication
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 5/003 Kits for diabetics
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: A61M 5/31568 Means keeping track of the total dose administered, e.g. since the cartridge was inserted
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 40/60 for the operation of medical equipment or devices

Abstract

The embodiments described herein may relate to methods and systems for adjusting insulin delivery. Some methods and systems may be configured to adjust insulin delivery to personalize automated insulin delivery for a person with diabetes. Such personalization may include adjusting user specific dosage parameters in response to a user provided insulin delivery amount, including a user provided insulin delivery amount that varies from a recommended insulin delivery amount.

Claims

1. A method, comprising:

receiving a user specified bolus dose of insulin that is different than a recommended bolus dose of insulin;

determining a meal component of the user specified bolus dose of insulin;

adjusting one or more user specific dosage parameters based on the determined meal component;

determining a future blood glucose level for a time interval based on the adjusted one or more user specific dosage parameters;

determining a basal insulin delivery for the time interval based on the determined future blood glucose level; and

configuring an insulin delivery system to deliver insulin during the time interval according to the determined basal insulin delivery.

2. The method of claim 1, wherein determining a meal component of the user specified bolus dose of insulin comprises determining a carbohydrate blood glucose level by subtracting a correction blood glucose level from the user specified bolus dose of insulin, wherein the correction component is associated with the recommended bolus dose of insulin.

3. The method of claim 1, further comprising determining future blood glucose levels for a number of insulin delivery profiles.

4. The method of claim 3, wherein each insulin delivery profile comprises:

the time interval, wherein the time interval is defined by a start time, an end time, and a number of sub-time intervals between the start time and the end time, and

one or more insulin delivery actions, wherein each of the one or more insulin delivery actions is associated with a sub-time interval of the number of sub-time intervals.

5. The method of claim 4, further comprising selecting an insulin delivery profile responsive to a comparison of the determined future blood glucose levels and one or more target blood glucose levels.

6. The method of claim 4, wherein the time interval is a diurnal time interval.

7. The method of claim 1, wherein the one or more user specific dosage parameters are selected from a group comprising:

a carbohydrate to insulin ratio, an insulin sensitivity factor, and a daily basal rate.

8. The method of claim 1, wherein the one or more user specific dosage parameters are an amount of carbohydrates.

9. The method of claim 8, wherein the amount of carbohydrates is grams of carbohydrates.

10. The method of claim 1, further comprising:

determining an automated correction insulin delivery based on the one or more user specific dosage parameters; and

configuring the insulin delivery system to deliver insulin during the time interval according to the determined automated correction insulin delivery.

11. An insulin delivery system, comprising:

an insulin delivery device configured to deliver insulin to a user of the insulin delivery system;

a processing unit associated with the insulin delivery device, the processing unit configured to;

determine a meal component of a user specified bolus dose of insulin;

adjust one or more user specific dosage parameters based on the determined meal component;

determine a future blood glucose level for a time interval based on the adjusted one or more user specific dosage parameters;

determine a basal insulin delivery for the time interval based on the determined future blood glucose level; and

configure the insulin delivery device to deliver insulin during the time interval according to the determined basal insulin delivery.

12. The system of claim 11, wherein the one or more user specific dosage parameters are selected from a group comprising:

a carbohydrate to insulin ratio, an insulin sensitivity factor, and a daily basal rate.

13. The system of claim 11, wherein the one or more user specific dosage parameters are an amount of carbohydrates.

14. The system of claim 12, wherein the amount of carbohydrates is grams of carbohydrates.

15. The system of claim 11, further comprising a memory having stored thereon a number of insulin delivery profiles.

16. The system of claim 15, wherein each insulin delivery profile comprises:

the time interval, wherein the time interval is defined by a start time, an end time, and a number of sub-time intervals between the start time and the end time, and

one or more insulin delivery actions, wherein each of the one or more insulin delivery actions is associated with a sub-time interval of the number of sub-time intervals.

17. The system of claim 15, wherein the “

processing unit”

is further configured to determine future blood glucose levels for a number of insulin delivery profiles.

18. The system of claim 15, wherein the “

processing unit”

is further configured to select an insulin delivery profile responsive to a comparison of the determined future blood glucose levels and one or more target blood glucose levels.

19. The system of claim 15, wherein the insulin delivery device is configured to deliver insulin automatically.

20. A method, comprising:

displaying a dashboard comprising a number of display regions and a number of activatable regions, wherein the number of display regions are configured to display information to a user of an insulin delivery system, and further wherein the activatable regions are configured to permit the user to interact with the insulin delivery system;

providing a first insulin delivery schedule at a first display region;

providing a recommended bolus dose of insulin at a second display region;

receiving a user recommended bolus dose of insulin at a first activatable region, the user recommended bolus dose of insulin being different than the recommended bolus dose of insulin; and

providing a second insulin delivery schedule at the first display region, the second insulin delivery schedule associated with the user recommended bolus dose of insulin.

21. The method of claim 20, wherein each of the first insulin delivery schedule and the second insulin delivery schedule comprises:

at least one time interval having a start time, an end time, and a number of sub-time intervals between the start time and the end time; and

insulin delivery levels associated with the number of sub-time intervals.

22. The method of claim 21, wherein the at least one time interval is a diurnal time interval.

23. The method of claim 20, further comprising:

providing a user specific dosage parameter at a third display region; and

providing an adjusted user specific dosage parameter at the third display region.

24. The method of claim 23, wherein the user specific dosage parameter is selected from the group consisting of a carbohydrate to insulin ratio, an insulin sensitivity factor, and a daily basal rate.

25. The method of claim 24, wherein the user specified dosage parameter is an amount of carbohydrates.

26. The method of claim 25, wherein the amount of carbohydrates is grams of carbohydrates.

27. The method of claim 20, further comprising providing future blood glucose levels associated with at least one time interval at a third display region.