METHODS FOR THE SYNTHESIS OF FUNCTIONALIZED NUCLEIC ACIDS
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Abstract
Described herein are methods for the synthesis of derivatives of thiosulfonate reagents. Said reagents have utility for the synthesis of phosphorothiotriesters from H-phosphonates in a stereospecific fashion.
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1-18. -18. (canceled)
- 19. A thiosulfonate reagent of structure IIa:
- 26. A compound selected from
Specification