CRYOPRESERVATION DEVICES
First Claim
Patent Images
1. A vial assembly comprising:
- a tubular body comprising a cavity, a first end, a second end for dispensing a sample, and a tube wall comprising a first material; and
a flexible bottom comprising a second elastomeric material overmolded on an interior surface of the tube wall proximate the first end,wherein the flexible bottom does not extend past the first end of the tubular body.
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Accused Products
Abstract
Vial assemblies comprising a tubular body and a flexible bottom or flexible liner are described herein, wherein the flexible bottom or liner is configured to compress at least partially upon the application of force. Methods for storing and removing frozen samples from such vial assemblies are also described herein.
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Citations
24 Claims
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1. A vial assembly comprising:
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a tubular body comprising a cavity, a first end, a second end for dispensing a sample, and a tube wall comprising a first material; and a flexible bottom comprising a second elastomeric material overmolded on an interior surface of the tube wall proximate the first end, wherein the flexible bottom does not extend past the first end of the tubular body. - View Dependent Claims (2, 3, 4)
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5. A vial assembly comprising:
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a tubular body comprising a cavity, a first end, a second end, and a tube wall comprising a first material; and a flexible bottom comprising a second elastomeric material overmolded on the first end of the tubular body, wherein the flexible bottom further comprises at least two flanges attached to the tube wall and configured to hinge inwardly and apply force to a surface of the flexible bottom.
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6. A vial assembly comprising:
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a substantially rigid tubular body comprising a cavity, a first end, a second end, and a tube wall comprising a first material; and a flexible liner comprising a second elastomeric material positioned in the cavity of the tubular body and extending past the first end of the substantially rigid tubular body, wherein the flexible liner further comprises at least two flanges, and wherein the flanges are configured to hinge inwardly and apply force to a surface of the flexible liner. - View Dependent Claims (7, 8, 9)
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10. A vial assembly comprising:
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a tubular body comprising a cavity, a first end, a second end for dispensing a sample, a tube wall, and a flexible bottom disposed on an interior surface of the tube wall proximate the first end, wherein the tube wall and flexible bottom comprise a first material, wherein the flexible bottom has a first thickness less which is less than a second thickness of the tube wall, and wherein the flexible bottom does not extend past the first end of the tubular body. - View Dependent Claims (11, 12, 13, 14, 15, 16)
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17. A method for removing a frozen sample from a vial assembly comprising a tubular body having a first end, a second end for dispensing the frozen sample, and a flexible bottom overmolded on an interior surface of the tubular body proximate the first end, the method comprising:
applying force to at least a portion of the overmolded flexible bottom, wherein the flexible bottom is configured to compress at least partially upon the application of force. - View Dependent Claims (18, 19, 20)
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21. A method for removing a frozen sample from a vial assembly comprising a tubular body and a flexible liner inserted into a cavity of the tubular body, the method comprising:
depressing two or more flanges of the flexible liner to apply force to at least a portion of the flexible liner, wherein the flexible liner is configured to compress at least partially upon the application of force.
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22. A method for removing a frozen sample from a vial assembly comprising a tubular body comprising a tube wall, a first end, and a flexible bottom disposed proximate the first end, the method comprising:
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applying force to at least a portion of the flexible bottom, wherein the flexible bottom is configured to compress at least partially upon the application of force, wherein the tube wall and flexible bottom comprise a first material, and wherein the flexible bottom has a first thickness which is less than a second thickness of the tube wall. - View Dependent Claims (23, 24)
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Specification