COMPOSITIONS COMPRISING BACTERIAL STRAINS
First Claim
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1. A pharmaceutical composition comprising a therapeutically effective amount of a bacteria strain of the genus Erysipelatoclostridium;
- wherein the therapeutically effective amount of the bacteria strain is an amount sufficient to treat or prevent a condition mediated by an increase in at least one cytokine in a subject; and
wherein the bacterial strain is lyophilized and/or the pharmaceutical composition further comprises a pharmaceutically acceptable excipient, diluent, or carrier.
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Abstract
The invention provides compositions comprising bacterial strains for treating and preventing inflammatory and autoimmune diseases.
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Citations
30 Claims
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1. A pharmaceutical composition comprising a therapeutically effective amount of a bacteria strain of the genus Erysipelatoclostridium;
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wherein the therapeutically effective amount of the bacteria strain is an amount sufficient to treat or prevent a condition mediated by an increase in at least one cytokine in a subject; and wherein the bacterial strain is lyophilized and/or the pharmaceutical composition further comprises a pharmaceutically acceptable excipient, diluent, or carrier. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A food product that comprises:
- a therapeutically effective amount of a bacteria strain of the genus Erysipelatoclostridium; and
a nutritious product. - View Dependent Claims (18)
- a therapeutically effective amount of a bacteria strain of the genus Erysipelatoclostridium; and
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19. A method of treating or preventing a condition in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising a bacteria strain of the genus Erysipelatoclostridium;
- wherein the bacteria strain is present in an amount sufficient for treating or preventing a condition mediated by the Th17 pathway or by an increase in the IL-17 cytokine in the subject.
- View Dependent Claims (20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
Specification