DEVICE AND METHOD WITH REDUCED PACEMAKER RATE IN HEART VALVE REPLACEMENT

• US 20180289471A1
• Filed: 04/18/2016
• Published: 10/11/2018
• Est. Priority Date: 05/01/2015
• Status: Active Grant

• Current Assignee: JenaValve Technology, Inc.
• Original Assignee: JenaValve Technology, Inc.
• Inventors: SCHRECK, Stefan, RANGWALA, Hussain S., SAFFARI, Payam
• Granted Patent: US 10,709,555 B2
• Time in Patent Office: Days
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2210/0014 using shape memory or superelastic materials, e.g. nitinol
• CPC Class Codes: A61F 2230/0013 Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0056 W-shaped, e.g. M-shaped, sigma-shaped
• CPC Class Codes: A61F 2230/006 Y-shaped
• CPC Class Codes: A61F 2250/0032 differing in radiographic density
• CPC Class Codes: A61F 2250/0097 Visible markings, e.g. indicia
• CPC Class Codes: A61F 2250/0098 radio-opaque, e.g. radio-opaque markers
• CPC Class Codes: A61L 31/18 Materials at least partially X-ray or laser opaque

Abstract

The disclosure relates to heart valve prostheses with the reduced need of pacemaker implantation and improved means for positioning the replacement heart valve.

Claims

1. A heart valve prosthesis, comprising a stent component, a valve component, a seal, and at least one locator for positioning the prosthesis at a target site of an endogenous heart valve, wherein the prosthesis is expandable from a non-expanded state to an expanded state, and wherein in the expanded state a shortest distance between a proximal end of the locator and a proximal end of the prosthesis is less than 10 mm.

2. The prosthesis according to claim 1, wherein the locator comprises a probe.

3. The prosthesis according to claim 1, wherein the distance between the proximal end of the locator and the proximal end of the prosthesis varies in a circumferential direction of the prosthesis.

4. The prosthesis according to claim 1, wherein in the non-expanded state, the locator and the stent component extend along a tube perimeter, and in the expanded state, the locator extends at least partially outside an expanded tube perimeter.

5. The prosthesis according to claim 4, wherein in the expanded state, the locator is positioned in a proximal direction and at least partially radially outside of a portion of the stent component.

6. The prosthesis according to claim 5, wherein the distance between the proximal end of the locator and the proximal end of the stent component in the expanded state as compared to the non-expanded state differs by 1 mm, 2 mm, 3 mm, 4 mm, or 5 mm.

7. The prosthesis according to claim 6, wherein the locator comprises an arch attached to, or forming an integral part of, the stent component.

8. The prosthesis according to claim 7, wherein the arch of the locator has two ends, and wherein each end is attached to, or forms an integral part of, a fastening arch of the stent component.

10. The prosthesis according to claim 1, wherein the prosthesis is configured to not cover one or more coronary arteries when placed at the target site when in the expanded state.

12. The prosthesis according to claim 1, wherein the stent component comprises three sections including a first section that corresponds to a right coronary sinus (RCS), a second section that corresponds to a left coronary sinus (LCS), and a third section that corresponds to a non-coronary coronary sinus (NCS), wherein the three sections each comprise a distal end and a proximal end;

and wherein;

the proximal end of each section extends with an equal length so that the sections corresponding to the RCS, LCS, and NCS end at the same level, or

the proximal ends corresponding to the RCS and LCS sections are shorter than the proximal end of the NCS section.

13. The prosthesis according to claim 12, wherein the proximal end of each section extends with an equal length so that the sections corresponding to the RCS, LCS, and NCS end at the same level, and wherein the NCS proximal section comprises an indentation.

14. The prosthesis according to claim 1, further comprising a deformable indicator.

15. The prosthesis according to claim 14, wherein the indicator comprises one or more wires or antennas.

16. The prosthesis according to claim 14, wherein the indicator comprises a radiopaque material.

17. The prosthesis according to claim 14, wherein the stent component comprises a counterpart to the indicator.

18. The prosthesis according to claim 17, wherein the counterpart comprises the at least one locator, a feeler, a hook, or a rim;

and wherein the counterpart has a U, V, Y, M or W shape.

19. The prosthesis according to claim 18, wherein the indicator and the counterpart comprise the same materials.

20. The prosthesis according to claim 17, wherein the counterpart comprises a radiopaque material.

21. The prosthesis according to claim 1, wherein the prosthesis comprises nitinol, soft fabric, textile, mammalian tissue, a polymer, or a combination thereof.

22. The prosthesis according to claim 1, wherein the prosthesis is an aortic heart valve or a mitral heart valve.

9. (canceled)

11. (canceled)

23. (canceled)

24. (canceled)