METHODS FOR GENERATING HYBRID ANALYTE LEVEL OUTPUT, AND DEVICES AND SYSTEMS RELATED THERETO
First Claim
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1. A method of generating a hybrid analyte level output, comprising:
- receiving continuous sensor data comprising uncompensated analyte levels received from an in vivo sensor integrated with a drug delivery system, the uncompensated analyte levels comprising interstitial fluid glucose levels;
deriving lag-compensated analyte levels from the uncompensated analyte levels using a processor, the lag-compensated analyte levels comprising estimated blood glucose levels; and
generating the hybrid analyte level output comprised of the uncompensated analyte levels and the lag-compensated analyte levels using the processor, wherein the uncompensated analyte levels lag in time with respect to the lag-compensated analyte levels;
wherein the hybrid analyte level output tracks between the uncompensated analyte levels and the lag-compensated analyte levels according to predetermined criteria, the predetermined criteria comprising;
criteria for tracking the uncompensated analyte levels when selected analyte levels are below a predetermined threshold and have been rising for at least a predetermined duration of time;
criteria for tracking the lag-compensated analyte levels when the selected analyte levels are not below the predetermined threshold or have not been rising for at least the predetermined duration of time; and
wherein the drug delivery system is configured to administer insulin based on the hybrid analyte level output.
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Abstract
Generally, methods, devices, and systems for generating a hybrid analyte level output are provided. The uncompensated analyte levels lag in time with respect to the lag-compensated analyte levels, and the hybrid analyte level output tracks between the uncompensated analyte levels and the lag-compensated analyte levels according to predetermined criteria.
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20 Claims
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1. A method of generating a hybrid analyte level output, comprising:
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receiving continuous sensor data comprising uncompensated analyte levels received from an in vivo sensor integrated with a drug delivery system, the uncompensated analyte levels comprising interstitial fluid glucose levels; deriving lag-compensated analyte levels from the uncompensated analyte levels using a processor, the lag-compensated analyte levels comprising estimated blood glucose levels; and generating the hybrid analyte level output comprised of the uncompensated analyte levels and the lag-compensated analyte levels using the processor, wherein the uncompensated analyte levels lag in time with respect to the lag-compensated analyte levels; wherein the hybrid analyte level output tracks between the uncompensated analyte levels and the lag-compensated analyte levels according to predetermined criteria, the predetermined criteria comprising; criteria for tracking the uncompensated analyte levels when selected analyte levels are below a predetermined threshold and have been rising for at least a predetermined duration of time; criteria for tracking the lag-compensated analyte levels when the selected analyte levels are not below the predetermined threshold or have not been rising for at least the predetermined duration of time; and wherein the drug delivery system is configured to administer insulin based on the hybrid analyte level output. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. An analyte monitoring device, comprising:
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a processor; and non-transitory memory operably coupled to the processor, the non-transitory memory including instructions stored therein that, when executed by the processor, cause the processor to; receive continuous sensor data comprising uncompensated analyte levels received from an in vivo sensor integrated with a drug delivery system, the uncompensated analyte levels comprising interstitial fluid glucose levels; derive lag-compensated analyte levels from the uncompensated analyte levels, the lag-compensated analyte levels comprising estimated blood glucose levels; and generate a hybrid analyte level output comprised of the uncompensated analyte levels and the lag-compensated analyte levels, wherein the uncompensated analyte levels lag in time with respect to the lag-compensated analyte levels; wherein the hybrid analyte level output tracks between the uncompensated analyte levels and the lag-compensated analyte levels according to predetermined criteria, the predetermined criteria comprising; criteria for tracking the uncompensated analyte levels when selected analyte levels are below a predetermined threshold and have been rising for at least a predetermined duration of time; criteria for tracking the lag-compensated analyte levels when the selected analyte levels are not below the predetermined threshold or have not been rising for at least the predetermined duration of time; and wherein the drug delivery system is configured to administer insulin based on the hybrid analyte level output. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20)
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Specification