PROSTHETIC VALVE FOR REPLACING A MITRAL VALVE

• US 20180296336A1
• Filed: 06/21/2018
• Published: 10/18/2018
• Est. Priority Date: 06/06/2014
• Status: Active Grant

• Current Assignee: Edwards Lifesciences Corporation
• Original Assignee: Edwards Lifesciences Corporation
• Inventors: Cooper, Alexander H., Peterson, Matthew A., Brunnett, William C.
• Granted Patent: US 10,687,939 B2
• Time in Patent Office: Days
• CPC Class Codes: A61F 2/2409 Support rings therefor, e.g. for connecting valves to tissue annuloplasty rings A61F2/2442
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2002/9534 for repositioning of stents
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0065 toroidal, e.g. ring-shaped, doughnut-shaped
• CPC Class Codes: A61F 2230/0078 hyperboloidal

Abstract

Embodiments of a prosthetic heart valve comprise an annular main body, an atrial cap extending radially outwardly from the atrial end of the main body, and a plurality of ventricular anchors extending outwardly from the ventricular end of the main body. Each ventricular anchor can have a proximal end portion connected to the ventricular end, an intermediate portion extending away from the atrial end and then back toward the atrial so as to define a first bend, and a free distal end portion that extends from the intermediate portion. The distal end portion can comprise a first section, a second section, and a second bend between the first and second sections, the first section extending from the intermediate portion in a direction toward the atrial end and radially away from the main body.

Claims

1. A prosthetic valve for implanting at a native mitral or tricuspid valve region of the heart, the native valve region having a native valve annulus and native leaflets, the prosthetic valve comprising:

a radially compressible and expandable frame comprising a double-body structure including an annular inner frame portion and an annular outer frame portion overlapping the inner frame portion, one of inner frame portion and the outer frame portion being more flexible than the other; and

a plurality of prosthetic leaflets supported within the inner frame portion for regulating the flow of blood in one direction through the frame.

2. The prosthetic valve of claim 1, wherein the outer frame portion is more flexible than the inner frame portion.

3. The prosthetic valve of claim 1, wherein the inner frame portion is more flexible than the outer frame portion.

4. The prosthetic valve of claim 1, wherein the frame comprises an atrial portion extending radially outwardly from one of the inner and outer frame portions and configured to be deployed in an atrium of the heart upstream of the native valve annulus.

5. The prosthetic valve of claim 4, wherein the atrial portion comprises an atrial sealing cap, which after being deployed, blocks the flow of blood between the native leaflets and the outside of the frame.

6. The prosthetic valve of claim 1, wherein the frame comprises a plurality of ventricular anchors extending from one of the inner and outer frame portions, the ventricular anchors configured to engage tissue in a ventricle of the heart downstream of the native valve annulus.

7. The prosthetic valve of claim 6, wherein the ventricular anchors extend from the inner frame portion.

8. The prosthetic valve of claim 1, wherein the inner frame portion and the outer frame portion are connected to each other with sutures.

9. The prosthetic valve of claim 1, wherein the inner frame portion and the outer frame portion are connected to each other with pins.

10. A prosthetic valve for implanting at a native mitral or tricuspid valve region of the heart, the native valve region having a native valve annulus and native leaflets, the prosthetic valve comprising:

a radially compressible and expandable frame comprising a double-body structure including an annular inner frame portion and an annular outer frame portion overlapping the inner frame portion, wherein the inner frame portion and the outer frame portion are connected to each other with pins; and

a plurality of prosthetic leaflets supported within the inner frame portion for regulating the flow of blood in one direction through the frame.

11. The prosthetic valve of claim 10, wherein one of inner frame portion and the outer frame portion is more flexible than the other.

12. The prosthetic valve of claim 10, wherein the frame further comprises an atrial portion configured anchor the prosthetic valve against migration in a downstream direction and a ventricular portion configured to anchor the prosthetic valve against migration in an upstream direction.

13. The prosthetic valve of claim 12, wherein the ventricular portion extends from a downstream outlet end of the annular inner frame portion and the atrial portion extends from an upstream inlet end of the annular outer frame portion.

14. A prosthetic valve for implanting at a native mitral or tricuspid valve region of the heart, the native valve region having a native valve annulus and native leaflets, the prosthetic valve comprising:

a radially compressible and expandable frame comprising a double-body structure including an annular inner frame portion and an annular outer frame portion overlapping the inner frame portion, the frame further comprising a plurality of ventricular anchors extending outwardly from an outlet end of the annular inner frame portion, the ventricular anchors being configured to engage tissue in a ventricle of the heart; and

a plurality of prosthetic leaflets supported within the inner frame portion for regulating the flow of blood in one direction through the frame.

15. The prosthetic valve of claim 14, wherein the ventricular anchors are connected to the annular inner frame portion independently of each other without frame segments interconnecting adjacent ventricular anchors.

16. The prosthetic valve of claim 14, wherein the frame further comprises an atrial portion extending radially outwardly from the annular outer frame portion.

17. The prosthetic valve of claim 14, wherein an inner surface of the annular outer frame portion is secured against an outer surface of the annular inner frame portion.

18. The prosthetic valve of claim 17, wherein the annular inner frame portion and the annular outer frame portion are connected to each other with sutures.

19. The prosthetic valve of claim 14, wherein the ventricular anchors are curved in a direction extending toward an inlet end of the frame.

20. The prosthetic valve of claim 19, wherein the ventricular anchors extend alongside an outer surface of the annular outer frame portion.