REPLACEMENT MITRAL VALVES

• US 20180296341A1
• Filed: 06/19/2018
• Published: 10/18/2018
• Est. Priority Date: 01/23/2017
• Status: Active Grant

• Current Assignee: Cephea Valve Technologies, Inc. (Abbott Laboratories Incorporated)
• Original Assignee: Cephea Valve Technologies, Inc. (Abbott Laboratories Incorporated)
• Inventors: NOE, Spencer, WALLACE, Dan, OAKDEN, Jonathan
• Granted Patent: US 10,368,990 B2
• Time in Patent Office: Days
• CPC Class Codes: A61F 2/2409 Support rings therefor, e.g. for connecting valves to tissue annuloplasty rings A61F2/2442
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2445 Annuloplasty rings in direct contact with the valve annulus
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/0041 using additional screws, bolts, dowels or rivets, e.g. connecting screws
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/001 Figure-8-shaped, e.g. hourglass-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0065 toroidal, e.g. ring-shaped, doughnut-shaped
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61F 2250/006 modular
• CPC Class Codes: A61F 2250/0063 Nested prosthetic parts
• CPC Class Codes: A61M 39/22 Valves or arrangement of valves A61M39/02, A61M39/0247, A61M39/16 take precedence; regulating valves in infusion systems A61M5/16881; in devices worn by the patient for the reception of urine, faeces, catamenial or other discharge, or in colostomy devices A61F5/4405

Abstract

A prosthetic mitral valve includes an anchor assembly, a strut frame, and a plurality of replacement leaflets secured to the annular strut frame. The anchor assembly includes a ventricular anchor, an atrial anchor, and a central portion therebetween. The ventricular anchor and the atrial anchor are configured to flare radially outwards relative to the central portion. The annular strut frame is disposed radially within the anchor assembly and is attached to the anchor assembly. The central portion is configured to align with a native valve orifice and the ventricular anchor and the atrial anchor are configured to compress native cardiac tissue therebetween.

Claims

1. A prosthetic mitral valve comprising:

a valve support assembly comprising a ventricular anchor, a central portion, and an atrial anchor, the valve support assembly configured to self-expand from a collapsed configuration to an expanded configuration;

a plurality of leaflets secured to the valve support assembly; and

a plurality of retention hooks attached to the ventricular anchor, wherein each of the retention hooks curves radially outwards to point in an atrial direction when the valve support assembly is in the expanded configuration, each retention hook having a ratio of radius of curvature to thickness of 4;

1 or greater.

2. The prosthetic mitral valve of claim 1, wherein the ratio is between 4:

1 and 8;

1.

3. The prosthetic mitral valve of claim 1, wherein each of the plurality of retention hooks is configured to point at an angle of 10-40 degrees relative to a central longitudinal axis of the prosthetic mitral valve.

4. The prosthetic mitral valve of claim 3, wherein the angle is approximately 28°

.

5. The prosthetic mitral valve of claim 1, wherein a radius of curvature of each of the plurality of retention hooks is less than 4 mm.

6. The prosthetic mitral valve of claim 1, wherein a radius of curvature of each of the plurality of retention hooks is between 2 mm-4 mm.

7. The prosthetic mitral valve of claim 1, wherein a thickness of each of the plurality of retention hooks is less than 1.6 mm.

8. The prosthetic mitral valve of claim 1, wherein a thickness of each retention hooks is between 0.25 mm and 1 mm.

9. The prosthetic mitral valve of claim 1, wherein a ratio of width to thickness of each retention hook is between 0.3:

1 and 1;

1.

10. The prosthetic mitral valve of claim 1, wherein each hook is configured to engage approximately 3-10 mm of mitral valve tissue when the valve support assembly is in the expanded configuration.

11. The prosthetic mitral valve of claim 1, wherein the plurality of retention hooks are integral with the valve support assembly.

12. The prosthetic mitral valve of claim 1, wherein the valve support assembly includes an anchor assembly comprising the ventricular and atrial anchors and the central portion and an annular strut frame positioned radially within the anchor assembly.

13. The prosthetic mitral valve of claim 12, wherein the plurality of retention hooks are attached to the anchor assembly.

14. The prosthetic mitral valve of claim 1, wherein the central portion is configured to align with a native valve orifice, and wherein the ventricular anchor and the atrial anchors are configured to compress native cardiac tissue therebetween.

15. The prosthetic mitral valve of claim 1, wherein the valve support assembly comprises a plurality of diamond-shaped cells, wherein each of the retention hooks extends from an apex of an interior diamond-shaped cell.

16. The prosthetic mitral valve of claim 15, wherein a retention hook extends from each apex in a circumferential line around the prosthetic mitral valve except a position closest to a leaflet attachment point.

17. A prosthetic mitral valve comprising:

a valve support assembly comprising a ventricular anchor, a central portion, and an atrial anchor;

a plurality of leaflets secured to the valve support assembly; and

a plurality of retention hooks attached to the ventricular anchor, wherein each of the retention hooks curves radially outwards to point in an atrial direction, each retention hook having a ratio of radius of curvature to thickness of greater than 4;

1 and points at an angle of 10°

-40°

relative to a central longitudinal axis of the prosthetic mitral valve.

18. The prosthetic mitral valve of claim 17, wherein a ratio of width to thickness of each retention hook is between 0.3:

1 and 1;

1.

19. The prosthetic mitral valve of claim 17, wherein each hook is configured to engage approximately 3-10 mm of mitral valve tissue when the valve support assembly is in the expanded configuration.

20. The prosthetic mitral valve of claim 17, wherein a radius of curvature of each of the plurality of retention hooks is less than 4 mm.