Atrio-Ventricular Valve Stent with Native Leaflet Grasping and Holding Mechanism

• US 20180303612A1
• Filed: 06/03/2016
• Published: 10/25/2018
• Est. Priority Date: 06/04/2015
• Status: Active Grant

• Current Assignee: Epygon
• Original Assignee: Epygon
• Inventors: Pasquino, Enrico, Scorsin, Marcio, Pasquino, Stefano, Marchisio, Andrea, Valerio, Lorenzo, Casalegno, Sergio, Gard, Marco, Arru, Pietro
• Granted Patent: US 10,806,577 B2
• Time in Patent Office: Days
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2448 D-shaped rings
• CPC Class Codes: A61F 2210/0014 using shape memory or superelastic materials, e.g. nitinol
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2230/0034 D-shaped

Abstract

Atrio-ventricular valve stent (1) having a tubular shape, with a sub annular anterior side (2), a sub annular posterior side (3) and sub annular lateral sides (13), the sub annular anterior side (2) comprising a self-folding native leaflet engagement member (4-9) that forms a straight extension of said sub annular anterior side (2) when the stent (1) is collapsed and that is folded on itself when the stent (1) is in an expanded state; said engagement member (4-9) forming an integral part of the stent (1) and wherein each sub annular lateral side (13) is longer than said sub annular anterior side (2) when the stent (1) is in an expanded state.

Claims

1-25. -25. (canceled)

26. An atrio-ventricular valve stent having a tubular shape comprising:

a sub annular anterior side;

a sub annular posterior side; and

a plurality of sub annular lateral sides,

wherein the sub annular anterior side includes a self-folding native leaflet engagement member that forms a straight extension of the sub annular anterior side when the stent is in a collapsed state and folds on itself when the stent is in an expanded state,

wherein the self-folding native leaflet engagement member forms an integral part of the stent, and

wherein each one of the plurality of sub annular lateral sides is longer than the sub annular anterior side when the stent is in the expanded state.

27. The atrio-ventricular valve stent according to claim 26, wherein each one of the plurality of sub annular lateral side is longer than the sub annular posterior side when the stent is in the expanded state.

28. The atrio-ventricular valve stent according to claim 26, wherein the sub annular posterior side is longer than the sub annular anterior side when the stent is in the expanded state.

29. The atrio-ventricular valve stent according to claim 26, wherein the sub annular posterior side is shorter than the sub annular anterior side when the stent is in the expanded state.

30. The atrio-ventricular valve stent according to claim 26, wherein the sub annular posterior side and the sub annular anterior side have a same length when the stent is in the expanded state.

31. The atrio-ventricular valve stent according to claim 26, the stent having a D-shaped cross section.

32. The atrio-ventricular valve stent according to claim 26, wherein the self-folding native leaflet engagement member and the sub annular anterior side are linked via a single point.

33. The atrio-ventricular valve stent according to claim 26, wherein the self-folding native leaflet engagement member includes a foldable portion having at least one wavy line.

34. The atrio-ventricular valve stent according to claim 33, wherein the at least one wavy line comprises:

a first and a second symmetric wavy line,

wherein a wave formed by the first symmetric wavy line is linked to a wave of the second symmetric wavy line by a bridge.

35. The atrio-ventricular valve stent according to claim 26, wherein the engagement member includes a free end that is flared.

36. The atrio-ventricular valve stent according to claim 26, further comprising:

an anterior native valve locking system including a self-orienting extension body that forms an integral part of the stent and that is located within the sub annular anterior side,

wherein the self-orienting extension body coincides with the sub annular anterior side when the stent is in the collapsed state and the self-orienting extension body is oriented in another direction when the stent is in the expanded state.

37. The atrio-ventricular valve stent according to claim 36, wherein the self-orienting extension body is oriented at approximately 30°

towards proximal end of the sub annular anterior side when the stent is in the expanded state.

38. The atrio-ventricular valve stent according to claim 26 further comprising:

a plurality of engagement members.

39. The atrio-ventricular valve stent according to claim 26 further comprising:

a native posterior leaflet engagement member located on the stent posterior side.

40. The atrio-ventricular valve stent according to claim 36 further comprising:

a posterior native valve locking system made of the self-orienting extension body that forms an integral part of the stent and that is located within the sub annular posterior side, the self-orienting extension body coinciding with the sub annular posterior side when the stent is in a collapsed state and the self-orienting extension body oriented in another direction when the stent is in the expanded state.

41. The atrio-ventricular valve stent according to claim 36, wherein the self-orienting extension body is surrounded by a window frame, and

wherein one end of the extension body is fixed to one side of the window frame.

42. The atrio-ventricular valve stent according to claim 41, wherein the window frame coincides with a wall of the stent when the stent is in the collapsed state and does not coincide with the wall of the stent when the stent is in the expanded state.

43. The atrio-ventricular valve stent according to claim 41, wherein the self-orienting extension body is fixed to an upper side or to a lower side of the window frame.

44. The atrio-ventricular valve stent according to claim 36, wherein the self-orienting extension body forms an angle between 60°

and 20°

with the frame when the stent is in the expanded state.

45. The atrio-ventricular valve stent according to claim 36, wherein the self-orienting extension body forms an angle between 5°

and 30°

with the frame when the stent is in the expanded state.

46. The atrio-ventricular valve stent according to claim 42, wherein the self-orienting extension body forms an angle between 150°

and 180°

with the wall of the stent when the stent is in the expanded state.

47. The atrio-ventricular valve stent according to claim 36, wherein the self-orienting extension body is entirely made of a flat blade.

48. The atrio-ventricular valve stent according to claim 34, wherein the bridge is covered by a sleeve.

49. The atrio-ventricular valve stent according to claim 47, wherein an end of the flat blade is covered by a cap.