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Profiling of Pathology Images for Clinical Applications

  • US 20180374210A1
  • Filed: 11/15/2016
  • Published: 12/27/2018
  • Est. Priority Date: 11/17/2015
  • Status: Active Grant
First Claim
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1. A computerized method for classifying tissue characteristics in digital pathology images, comprising the steps of:

  • (a) obtaining a digital pathology image of a tissue from a subject;

    (b) dividing the digital pathology image into tiles;

    (c) extracting primary features from the tiles in step (b), the primary features comprising shape, color, and texture features in the image;

    (d) grouping similar tiles into a number of sets based on similarity of the primary features;

    (e) selecting a representative tile from each set in step (d);

    (f) extracting secondary features from selected tiles from step (e), wherein the secondary features refine primary features;

    (g) assigning values to selected tiles, based on secondary features; and

    (h) comparing the values in step (g) to values in a reference.

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