BLOOD FILTRATION SYSTEM CONTAINING MANNOSE COATED SUBSTRATE
First Claim
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1. A method for attaching a mannose to an amine containing substrate, said method comprising:
- contacting an aminated substrate with an aqueous solution containing a mannose to form a Schiff base intermediate; and
contacting the Schiff base with a reducing agent to attach said mannose.
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Abstract
A blood filtration method, system, device and media for removing gram negative bacteria from the blood wherein the media includes a substrate coated with mannose optionally in constitution with substrate coated with heparin.
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14 Claims
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1. A method for attaching a mannose to an amine containing substrate, said method comprising:
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contacting an aminated substrate with an aqueous solution containing a mannose to form a Schiff base intermediate; and contacting the Schiff base with a reducing agent to attach said mannose. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification