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METHODS FOR PREPARING N-(4-FLUOROBENZYL)-N-(1-METHYLPIPERIDIN-4-YL)-N'-(4-(2-METHYLPROPYLOXY)PHENYLMETHYL)CARBAMIDE AND ITS TARTRATE SALT AND POLYMORPHIC FORM

  • US 20190047955A1
  • Filed: 07/19/2016
  • Published: 02/14/2019
  • Est. Priority Date: 07/20/2015
  • Status: Active Grant
First Claim
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1. A method of preparing pimavanserin (N-(4-fluorophenylmethyl)-N-(1 -methylpiperidin-4-yl)-N′

  • -(4-(2-methylpropyloxy)phenylmethyl)carbamide) or a salt thereof, the method comprising;

    contacting an intermediate according to Formula (A2),

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