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NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST ESOPHAGEAL CANCER AND OTHER CANCERS

  • US 20190177397A1
  • Filed: 02/21/2019
  • Published: 06/13/2019
  • Est. Priority Date: 07/06/2015
  • Status: Active Grant
First Claim
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1. A method of treating a patient who has cancer, comprising administering to said patient a composition comprising a population of activated T cells that kill the cancer cells in the patient that aberrantly express a peptide, wherein said peptide consists of the amino acid sequence selected from the group consisting of SEQ ID NO:

  • 2, SEQ ID NO;

    1, from SEQ ID NO;

    3 to SEQ ID NO;

    6, SEQ ID NO;

    8, SEQ ID NO;

    10, from SEQ ID NO;

    14 to SEQ ID NO;

    25, from SEQ ID NO;

    27 to SEQ ID NO;

    31, from SEQ ID NO;

    33 to SEQ ID NO;

    66, from SEQ ID NO;

    68 to SEQ ID NO;

    76, and from SEQ ID NO;

    78 to SEQ ID NO;

    101, wherein said cancer is selected from the group consisting of esophageal cancer, lung cancer, urinary bladder cancer, ovarian cancer, melanoma, uterine cancer, hepatocellular cancer, renal cell cancer, brain cancer, colorectal cancer, breast cancer, gastric cancer, pancreatic cancer, gallbladder cancer, bile duct cancer, prostate cancer, and leukemia.

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