SYNTHESIS OF INHIBITORS OF EZH2
First Claim
Patent Images
1. A method for preparing a diastereomerically enriched sulfinamide compound having the formula:
1 Assignment
0 Petitions
Accused Products
Abstract
Provided herein are synthetic methods for the preparation of EZH2 inhibitors.
0 Citations
33 Claims
- 1. A method for preparing a diastereomerically enriched sulfinamide compound having the formula:
-
5. (canceled)
-
8-11. -11. (canceled)
- 12. A method for preparing an optically active amine compound having the following formula:
-
13. (canceled)
-
16. (canceled)
-
18. (canceled)
- 19. A method for preparing an optically active enamine compound of the formula:
- 20. A method for preparing an optically active indole compound of the formula:
-
21. (canceled)
-
23. (canceled)
-
25. (canceled)
- 26. A method for preparing an optically active indole pyridine-one having the formula:
-
27. (canceled)
-
29. (canceled)
Specification