METHODS AND COMPOSITIONS FOR TREATING HYPERHIDROSIS
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Abstract
Aspects of the disclosure include methods for treating hyperhidrosis in a subject with a composition including a muscarinic antagonist and a muscarinic agonist. In practicing methods according to certain embodiments, a therapeutically effective amount of a composition including a muscarinic antagonist or a pharmaceutically acceptable salt thereof and a muscarinic agonist or a pharmaceutically acceptable salt thereof is administered to a subject and is sufficient to reduce hyperhidrosis in the subject and to reduce a dry mouth side effect of the muscarinic antagonist. Compositions for practicing the subject methods are also described as well as dose units containing one or more of the subject compositions.
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Citations
48 Claims
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1-30. -30. (canceled)
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31. A method of treating hyperhidrosis in a subject in need thereof, the method comprising:
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orally administering to the subject once per day or twice per day a single unit dose of a therapeutically effective amount of a composition comprising an immediate release formulation of about 1 mg to 10 mg of oxybutynin, or a pharmaceutically acceptable salt thereof, and a delayed-immediate release formulation of about 1 mg to 10 mg of pilocarpine, or a pharmaceutically acceptable salt thereof. - View Dependent Claims (32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48)
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Specification