Method and System for Treating Cancer and Other Age-Related Diseases by Extending the Healthspan of a Human
First Claim
1. A method of treating bladder cancer in a subject in need of such treatment, said method comprising administering to a microbiome of a subject with bladder cancer an effective amount of a bacterial composition comprising Bacillus calmette-guerin, said bacterial composition adapted to produce tomatidine and rapamycin.
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Abstract
Various embodiments of the present invention are directed to the field of Oncology, and in particular, embodiments directed to a method of ameliorating, treating, or preventing a malignancy in a human subject wherein the steps of the method assist or boost the immune system in eradicating cancerous cells. Certain embodiments are directed to the field of human longevity and aging in a manner such that cancer is not contracted due to ameliorating, treating, or reducing aging by increasing the healthspan and lifespan of humans. In certain embodiments, administration of beneficial bacteria to an individual'"'"'s microbiome that have been modified so as to produce effective amounts of desired compositions, compounds, agents, e.g. tomatidine, rapamycin, p53 protein, statins, etc., is employed to treat and prevent cancer and other age-related diseases.
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Citations
20 Claims
- 1. A method of treating bladder cancer in a subject in need of such treatment, said method comprising administering to a microbiome of a subject with bladder cancer an effective amount of a bacterial composition comprising Bacillus calmette-guerin, said bacterial composition adapted to produce tomatidine and rapamycin.
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13. A method of treating bladder cancer in a subject in need of such treatment, said method comprising administering to a microbiome of a subject with bladder cancer an effective amount of a bacterial composition comprising a bacteria that has been modified to express a therapeutically effective amount of tomatidine and rapamycin, said bacteria selected from the group consisting of Streptococcus, Actinomyces, Veillonella, Fusobacterium, Porphromonas, Prevotella, Treponema, Nisseria, Haemophilis, Eubacteria, Lactobacterium, Capnocytophaga, Eikenella, Leptotrichia, Peptostreptococcus, Staphylococcus, Propionibacterium, Chlamydia, Shigella flexneri, Mycoplasma bacteria, H. pylori, and Streptomyces hygroscopicus.
- 14. A method of treating bladder cancer in a subject in need of such treatment, said method comprising administering to a microbiome of a subject with bladder cancer an effective amount of a bacterial composition, said method comprising administering a therapeutically effective amount of bacteria of a species found in the subject'"'"'s gut microbiome, wherein the bacteria has been modified using a CRISPR-Cas system to produce one of tomatidine or rapamycin.
Specification