Fluid Delivery Device Needle Retraction Mechanisms, Cartridges and Expandable Hydraulic Fluid Seals

• US 20190307955A1
• Filed: 06/24/2019
• Published: 10/10/2019
• Est. Priority Date: 06/09/2010
• Status: Abandoned Application

• Current Assignee: Zealand Pharma A/S
• Original Assignee: Valeritas, Inc. (Zealand Pharma A/S)
• Inventors: Levesque, Steven F., Jenkins, Geoffrey H., Standley, Robert L., Johnson, Matthew P., Dube, JR., Daniel A.
• Application Number:
  US16/449,534
• Publication Number:
  US 20190307955A1
• Time in Patent Office: Days
• CPC Class Codes: A61M 2005/14252 with needle insertion means
• CPC Class Codes: A61M 2005/14256 with means for preventing access to the needle after use
• CPC Class Codes: A61M 2005/1586 Holding accessories for holding infusion needles on the body holding devices for catheters A61M25/02
• CPC Class Codes: A61M 2005/3123 having air entrapping or venting means, e.g. purging channels in pistons
• CPC Class Codes: A61M 2005/3128 Incorporating one-way valves, e.g. pressure-relief or non-return valves
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/14526 the piston being actuated by fluid pressure
• CPC Class Codes: A61M 5/158 Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
• CPC Class Codes: A61M 5/1684 by detecting the amount of infusate remaining, e.g. signalling end of infusion
• CPC Class Codes: A61M 5/322 Retractable needles, i.e. disconnected from and withdrawn into the syringe barrel by the piston devices for protecting guide needles in combination with catheters A61M25/0612
• CPC Class Codes: A61M 5/3232 Semi-automatic needle retraction, i.e. in which triggering of the needle retraction requires a deliberate action by the user, e.g. manual release of spring-biased retraction means
• CPC Class Codes: A61M 5/3234 Fully automatic needle retraction, i.e. in which triggering of the needle does not require a deliberate action by the user

Abstract

A fluid delivery device includes an automatic needle retraction mechanism configured to automatically retract a delivery end of a needle into a housing. In one embodiment, the needle assembly is configured to automatically withdraw the delivery end of the needle into the housing upon an actuator moving from the first position to the second position. In one embodiment, the needle assembly is configured to automatically withdraw the delivery end of the needle into the housing upon decoupling a bottom surface of the housing from a skin surface.

Claims

1-33. -33. (canceled)

34. A fluid delivery device comprising:

a housing having a first hydraulic chamber and a second hydraulic chamber;

a flow restrictor fluidly coupling the first hydraulic chamber and the second hydraulic chamber;

a cartridge having a container forming a fluid reservoir sealed at a proximal end with a piston, the cartridge being insertable into the housing and configured to couple the piston with the second hydraulic chamber, the fluid reservoir being substantially filled with a liquid prior to inserting the cartridge within the housing, the cartridge including a septum configured to be pierced by a delivery needle; and

an actuator coupled to the housing and configured to deliver a force to the piston through the first and second hydraulic chambers.

35. The fluid delivery device of claim 34, further comprising a cartridge seal coupled between the proximal end of the cartridge and the housing when the cartridge is inserted into the housing.

36. The fluid delivery device of claim 35, wherein the cartridge seal is compressible.

37. The fluid delivery device of claim 35 further comprising:

a hydraulic cap extending through the cartridge seal and coupling the piston and the second hydraulic chamber.

38. The fluid delivery device of claim 37, wherein the hydraulic cap is substantially rigid.

39. The fluid delivery device of claim 35, wherein the proximal end of the cartridge includes an overflow channel in fluid communication with the second hydraulic chamber when the cartridge is inserted into the housing.

40. The fluid delivery device of claim 39, wherein the overflow channel is formed between an outer peripheral edge of the proximal end of the cartridge and an inner peripheral edge of the proximal end of the cartridge, the outer peripheral edge extending axially further from the cartridge than the inner peripheral edge.

41. The fluid delivery device of claim 35, wherein the cartridge seal covers the second hydraulic reservoir prior to inserting the cartridge into the housing and the second hydraulic reservoir includes a piercing member configured to pierce the cartridge seal upon insertion of the cartridge into the housing.

42. The fluid delivery device of claim 41, wherein the piercing member includes a needle.

43. The fluid delivery device of claim 34, wherein the septum is slideably coupled with the container.

44. The fluid delivery device of claim 43, wherein the septum is configured to slide distally with respect to the container upon inserting the cartridge into the housing.

45. The cartridge of claim 43, wherein the septum includes a space for receiving an end of the delivery needle and a fluid passageway fluidly coupling the space and the fluid reservoir, the fluid passageway having a cross sectional area that is less than a cross sectional area of the space.

46. The cartridge of claim 43, wherein the septum seals a distal end of the container.

47. The cartridge of claim 43, wherein the septum is displaced with respect to the container when the septum is displaced upon inserting the cartridge into the housing.

47-1. The fluid delivery device of claim 34, wherein the cartridge includes a volume and a pressure, the volume being reduceable to enable insertion of the cartridge into the housing prior to engagement with the delivery needle and without changing the pressure.

48. The fluid delivery device of claim 34, wherein the second hydraulic chamber is configured to expel hydraulic fluid upon insertion of the cartridge into the housing.

49. The fluid delivery device of claim 34, wherein the cartridge further comprises a relief valve, the piston configured to expel air and/or fluid through the relief valve upon insertion of the cartridge into the housing.

50. The fluid delivery device of claim 34, wherein the cartridge further comprises a relief piston configured to slide distally upon insertion of the cartridge into the housing.

51. The fluid delivery device of claim 34, wherein the cartridge further comprises a septum configured to be pierced by the delivery needle.

52. The fluid delivery device of claim 34 further comprising:

a cap coupling the piston and the second hydraulic reservoir when the cartridge is inserted into the housing, the cap having a side wall and at least one of a top surface or a bottom surface that extends axially outwardly from the side wall, at least one of the top surface or the bottom surface being configured to invert upon inserting the cartridge into the housing.

53-62. -62. (Cancelled)

63. A fluid delivery device comprising:

a housing having a first hydraulic chamber and a second hydraulic chamber;

a flow restrictor fluidly coupling the first hydraulic chamber and a second hydraulic chamber;

a cartridge forming a fluid reservoir between a slideable piston and a stopper, the stopper configured to seal a distal end of the cartridge after the fluid reservoir is substantially filled with a liquid, the piston being coupled with the second hydraulic chamber; and

an actuator coupled to the housing and configured to deliver a force to the piston through the first and second hydraulic chambers.

64. The fluid delivery device of claim 63, wherein the cartridge includes a septum configured to receive a delivery needle.

65. A fluid delivery device comprising:

a housing having a first hydraulic chamber and a second hydraulic chamber;

a flow restrictor fluidly coupling the first hydraulic chamber and a second hydraulic chamber;

a fluid reservoir;

a seal sealing the second hydraulic chamber and configured to couple with the fluid reservoir, the seal being expandable between a compressed position and an expanded position; and

an actuator coupled to the first hydraulic chamber and configured to expand the seal and deliver a force to the fluid reservoir through the first and second hydraulic chambers.

66. The fluid delivery device of claim 65, wherein the cross sectional area of a distal end of the seal is smaller than the cross sectional area of a proximal end of the seal in the expanded position.

67. The fluid delivery device of claim 66, wherein the seal includes at least two telescoping members.

68. The fluid delivery device of claim 66, wherein the seal includes at least two cylindrical members having different diameters.

69. The fluid delivery device of claim 66, wherein the seal is generally conically shaped in the expanded position.

70. The fluid delivery device of claim 65 further comprising a cartridge having a container, a slideable piston and the fluid reservoir.