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AAV/UPR-plus virus, UPR-plus fusion protein, genetic treatment method and its use in treatment of neurodegenerative diseases, such as Parkinson's disease and Huntington's disease, among others

  • US 20190309324A1
  • Filed: 11/04/2016
  • Published: 10/10/2019
  • Est. Priority Date: 11/04/2015
  • Status: Active Grant
First Claim
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1. An adeno-associated vector (AAV), comprising a recombinant viral genome wherein said genome comprises an expression cassette comprising a transcription regulatory region specific for neuronal tissues operatively bound to a UPRplus polynucleotide of interest coding a fusion protein.

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