SYSTEM AND METHOD FOR REAL-TIME CREATION OF CARDIAC ELECTRO-PHYSIOLOGY SIGNALS IN THE HEART

• US 20190313910A1
• Filed: 11/03/2017
• Published: 10/17/2019
• Est. Priority Date: 11/08/2016
• Status: Active Grant

• Current Assignee: Koninklijke Philips N.V.
• Original Assignee: Koninklijke Philips N.V.
• Inventors: VIGNON, Francois Guy Gerard Marie, JAIN, Ameet Kumar
• Granted Patent: US 11,266,312 B2
• Time in Patent Office: Days
• CPC Class Codes: A61B 2034/105 Modelling of the patient, e.g. for ligaments or bones
• CPC Class Codes: A61B 2034/2051 Electromagnetic tracking systems
• CPC Class Codes: A61B 2034/2061 using shape-sensors, e.g. fiber shape sensors with Bragg gratings
• CPC Class Codes: A61B 2034/2063 Acoustic tracking systems, e.g. using ultrasound
• CPC Class Codes: A61B 2090/367 creating a 3D dataset from 2D images using position information
• CPC Class Codes: A61B 2090/378 using ultrasound
• CPC Class Codes: A61B 2562/0209 Special features of electrodes classified in A61B5/24, A61B5/25, A61B5/283, A61B5/291, A61B5/296, A61B5/053
• CPC Class Codes: A61B 5/0044 for the heart
• CPC Class Codes: A61B 5/066 Superposing sensor position on an image of the patient, e.g. obtained by ultrasound or x-ray imaging
• CPC Class Codes: A61B 5/285 Endotracheal, oesophageal or gastric probes
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/6858 with a distal basket, e.g. expandable basket
• CPC Class Codes: A61B 8/0841 for locating instruments
• CPC Class Codes: A61B 8/0883 for diagnosis of the heart
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/4254 using sensors mounted on the probe
• CPC Class Codes: A61B 90/37 Surgical systems with images on a monitor during operation

Abstract

An instrument for internal mapping includes a flexible elongated portion (702) and an expandable portion (710) coupled distally to the elongated portion, the expandable portion having one or more expandable loops. An array of sensors (706) and electrodes (708) is distributed on the expandable portion and is configured to concurrently register the instrument to real-time images of an anatomy using the sensors and measure electrical characteristics of the anatomy with the electrodes to generate an electro-physiology (EP) map having the anatomy and intensities of the electrical characteristics mapped together in the real-time images.

Claims

1. (canceled)

2. (canceled)

3. (canceled)

4. (canceled)

5. (canceled)

6. (canceled)

7. (canceled)

8. (canceled)

9. (canceled)

10. A system for internal mapping, comprising:

an instrument including a flexible elongated portion and an expandable portion coupled distally to the elongated portion, the expandable portion having one or more expandable loops and an array of sensors and electrodes distributed on the one or more expandable loops, the sensors configured to generate position data of the electrodes within an anatomy, the electrodes configured to generate electrical characteristics data of the anatomy;

an external imaging system configured to generate image data of an anatomy; and

a controller having an analysis module to concurrently receive the image data from the external imaging system, the position data from the sensors and the electrical characteristic data from the electrodes to register the image data and the electrical characteristics data based on the position data and to generate in real-time an electro anatomical map including an electrical map of the anatomy derived from the electrical characteristics data integrated with an anatomical map derived from the image data.

11. The system as recited in claim 10, wherein the electro-anatomical map further includes a mechanical activation map of the anatomy derived from the image data- and integrated with the electrical map and the anatomical map.

12. The system as recited in claim 10, wherein the electrical characteristics data includes one or more of voltage, charge and/or dipole density.

13. The system as recited in claim 10, further comprising a secondary navigation system configured to track the instrument within the anatomy.

14. The system as recited in claim 10, wherein the external imaging system includes an ultrasound system and the sensors include ultrasound sensors to determine a position of the instrument and the electrodes.

15. The system as recited in claim 10, wherein the controller includes a back propagation program that associates measured electrical characteristics of the anatomy derived from the electrical characteristic data with a structure or a surface of the anatomy derived from the image data.

16. The system as recited in claim 10, further comprising a display to display the electro-anatomical map to provide real-time feedback of anatomical changes as measured by the electrical characteristics data and the image data.

17. A method for electro anatomical mapping of an internal volume, the method comprising:

imaging, by an external imaging system, the internal volume having an instrument therein, the instrument including an array of electrodes and sensors distributed on one or more expandable loops of the instrument, the electrodes being locatable by the sensors;

registering, by a controller the instrument to the images of the internal volume using the sensors responsive to the external imaging system;

measuring, by the controller, electrical characteristics of the internal volume at the electrodes of the instrument;

back-propagating, by the controller, the measured electrical characteristics of the internal volume onto the imaging of the internal volume by the external system;

generating in-real time, by the controller, an electro-anatomical map including an electrical map of the anatomy derived from the measured electrical characteristics of the interval volume integrated with an anatomical map of the internal volume derived from the imaging of the internal volume by the external imaging system; and

displaying, by a display, the electro-anatomical map.

18. The method as recited in claim 17, wherein measuring, by the controller, of the electrical characteristics of the internal volume includes measuring the electrical characteristics of the internal volume with non-contact electrodes.

19. The method as recited in claim 17, wherein the displaying, by the display, of the electro-anatomical map includes displaying a real-time three-dimensional image of the internal volume with the electrical characteristics as feedback for a procedure.

20. The method as recited in claim 17, wherein the back-propagating, by the controller, of the measured electrical characteristics of the internal volume onto the imaging of the internal volume by the external imaging system includes an accounting, by the controller, for motion of the internal volume using a dynamic model which models the motion.

21. The method as recited in claim 17, further comprising obtaining, by the controller, mechanical deformation information of the internal volume from the imaging of the internal volume by the external imaging system;

and concurrently displaying, by the display, the mechanical deformation information and the electro-anatomical map.