Optical Detection And Measurement Of Hematocrit And Free Hemoglobin Concentration
First Claim
1. A method of measuring a hematocrit or a free hemoglobin concentration of a fluid, comprising:
- providing a fluid in a vessel;
exposing the fluid in the vessel to a light emitted by a broadband light source so as to cause at least a portion of the light to be reflected by the fluid;
receiving at least a portion of the reflected light;
analyzing at least a portion of the received light to determine a main wavelength of said at least a portion of the received light;
correlating the main wavelength to a hematocrit or a free hemoglobin concentration; and
generating an output indicative of the hematocrit or the free hemoglobin concentration corresponding to said main wavelength.
1 Assignment
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Accused Products
Abstract
A colorimetric optical sensor device includes a broadband light source configured to emit a light that is exposed to a fluid in a vessel. At least a portion of the light is reflected off of the fluid and received by an optical spectrometer. The optical spectrometer analyzes at least a portion of the received light to determine a main wavelength of the light. A controller correlates the main wavelength to a corresponding hematocrit or free hemoglobin concentration and generates an output indicative of the hematocrit or the free hemoglobin concentration of the fluid. The hematocrit or free hemoglobin concentration information may be used by a separation assembly in which the colorimetric optical sensor device may be incorporated to modify a separation procedure in which the monitored fluid is to be separated or is a component or constituent of a previously separated biological fluid.
1 Citation
25 Claims
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1. A method of measuring a hematocrit or a free hemoglobin concentration of a fluid, comprising:
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providing a fluid in a vessel; exposing the fluid in the vessel to a light emitted by a broadband light source so as to cause at least a portion of the light to be reflected by the fluid; receiving at least a portion of the reflected light; analyzing at least a portion of the received light to determine a main wavelength of said at least a portion of the received light; correlating the main wavelength to a hematocrit or a free hemoglobin concentration; and generating an output indicative of the hematocrit or the free hemoglobin concentration corresponding to said main wavelength. - View Dependent Claims (2, 3, 5, 6, 7, 10, 11, 12)
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4. (canceled)
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8-9. -9. (canceled)
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13. A colorimetric optical sensor device configured for use in combination with a fluid-containing vessel, the colorimetric optical sensor device comprising:
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a broadband light source configured to emit a light, with at least a portion of the light being exposed to a fluid in the vessel and reflected; an optical spectrometer configured to receive at least a portion of the reflected light and analyze at least a portion of the received light to determine a main wavelength of said at least a portion of the received light; and a controller configured to correlate the main wavelength to a hematocrit or a free hemoglobin concentration and generate an output indicative of the hematocrit or the free hemoglobin concentration corresponding to said main wavelength. - View Dependent Claims (14, 15, 17, 18, 19, 20, 21, 22, 23, 24)
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16. (canceled)
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25. (canceled)
Specification