FORMULATION FOR THE TREATMENT OF ACNE

• US 20190321329A1
• Filed: 04/18/2019
• Published: 10/24/2019
• Est. Priority Date: 08/28/2015
• Status: Abandoned Application

• Current Assignee: Akzo Nobel Chemicals International B.V. (Nouryon Coöperatief UA)
• Original Assignee: Akzo Nobel Chemicals International B.V. (Nouryon Coöperatief UA)
• Inventors: OPSAHL, Ross Christian, BUTUC, Steluta Gina
• Application Number:
  US16/387,726
• Publication Number:
  US 20190321329A1
• Time in Patent Office: Days
• CPC Class Codes: A61K 31/327 Peroxy compounds, e.g. hydroperoxides, peroxides, peroxyacids
• CPC Class Codes: A61K 47/08 containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
• CPC Class Codes: A61K 47/10 Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
• CPC Class Codes: A61K 47/36 Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
• CPC Class Codes: A61K 9/0014 Skin, i.e. galenical aspects of topical compositions non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00
• CPC Class Codes: A61K 9/06 Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels composition of ointments, creams or gels A61K47/00
• CPC Class Codes: A61K 9/10 Dispersions; Emulsions A61K9/06 takes precedence; composition of dispersions, emulsions A61K47/00
• CPC Class Codes: A61P 17/10 Anti-acne agents

Abstract

Peroxide of the formula

wherein R¹ is selected from linear and branched alkyl groups with 1-4 carbon atoms, and R², R³, and R⁴ are selected from hydrogen and linear and branched alkyl groups with 1-4 carbon atoms, for use as a medicament, in particular for the treatment of acne.

Claims

1. Skin-treatment formulation comprising:

a peroxide with the formula

2. Skin-treatment formulation according to claim 1 wherein the peroxide is di(4-methylbenzoyl)peroxide.

3. Skin-treatment formulation according to claim 1 wherein the peroxide is present in the formulation in a concentration of 0.1-20 wt %.

4. Skin-treatment formulation according to claim 1 wherein the dispersant system contains one or more compounds selected from suspending agent(s), gelling aid(s), buffering agent(s), defoamer(s), and dispersant(s).