TREATMENT FOR DUPUYTREN'S DISEASE
2 Assignments
0 Petitions
Accused Products
Abstract
Musculoskeletal fibroproliferative disorders, such as Dupuytren'"'"'s disease may be treated by administering locally a TNF-α antagonist. TNF-α antagonists find particular utility in inhibiting the progression of early disease state Dupuytren'"'"'s disease and other musculoskeletal fibroproliferative disorders and, in combination with extracellular matrix degradation agents (such as collagenase or matrix metalloproteinase I), treating advanced disease state Dupuytren'"'"'s disease and, in particular inhibiting recurrence.
0 Citations
57 Claims
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1-19. -19. (canceled)
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20. A method for treating a patient with early disease state periarticular fibrosis or adhesion comprising injecting an amount of a TNF-α
- antagonist effective to treat the patient directly at the site of the early disease state periarticular fibrosis or adhesion, so as to treat the patient.
- View Dependent Claims (48, 50, 51, 52, 53, 54, 55, 56, 57)
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21-47. -47. (canceled)
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49. A method of claim 49, wherein the TNF-α
- antagonist is an anti-TNF-α
antibody.
- antagonist is an anti-TNF-α
Specification