INTRATUMORAL VEIN-FORMATION PROMOTING AGENT
First Claim
1. A vein-formation promoting agent comprising a phosphatidylcholine as an active ingredient, the agent being capable of promoting vein-like morphological change of tumor vessels.
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Accused Products
Abstract
Provided are agents comprising a phosphatidylcholine as an active ingredient to serve as a vein-formation promoting agent capable of promoting vein-like morphological change of tumor vessels, a vessel-diameter enlarging agent capable of enlarging the diameter of tumor vessels, a blood vessel-connection promoting agent capable of promoting connection of tumor vessels to each other without mediation of a lysophospholipid receptor, a leukocyte-infiltration promoting agent capable of promoting infiltration of leukocytes throughout a tumor region without mediation of a lysophospholipid receptor, and an antitumor immunostimulatory agent capable of promoting infiltration of leukocytes throughout a tumor region without mediation of a lysophospholipid receptor.
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Citations
12 Claims
- 1. A vein-formation promoting agent comprising a phosphatidylcholine as an active ingredient, the agent being capable of promoting vein-like morphological change of tumor vessels.
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7. A vessel-diameter enlarging agent comprising a phosphatidylcholine as an active ingredient, the agent being capable of enlarging the diameter of tumor vessels.
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8. A blood vessel-connection promoting agent comprising a phosphatidylcholine as an active ingredient, the agent being capable of promoting connection of tumor vessels to each other without mediation of a lysophospholipid receptor.
- 9. A leukocyte-infiltration promoting agent comprising a phosphatidylcholine as an active ingredient, the agent being capable of promoting infiltration of leukocytes throughout a tumor region without mediation of a lysophospholipid receptor.
- 11. An antitumor immunostimulatory agent comprising a phosphatidylcholine as an active ingredient, the agent being capable of promoting infiltration of leukocytes throughout a tumor region without mediation of a lysophospholipid receptor.
Specification