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Constructs, Agents, and Methods for Facilitated Ablation of Cardiac Tissue

  • US 20190328877A1
  • Filed: 05/04/2017
  • Published: 10/31/2019
  • Est. Priority Date: 05/04/2016
  • Status: Active Grant
First Claim
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1. A method for augmenting ablation of a target tissue in a subject in need thereof, the method comprising:

  • (a) administering to a subject in need thereof an effective amount of an agent that modulates a protective and/or reparative cellular process induced in a target tissue by application of an ablative energy to the target tissue; and

    (b) applying an ablative energy to the target tissue in the subject, wherein the agent modulates the protective and/or reparative cellular process induced in the target tissue by application of the ablative energy to the target tissue, and augmenting ablation of the target tissue in the subject.

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