VALVE AND A METHOD FOR ADMINISTERING A PLURALITY OF DRUG FLUIDS

• US 20190328961A1
• Filed: 07/12/2019
• Published: 10/31/2019
• Est. Priority Date: 03/08/2016
• Status: Active Grant

• Current Assignee: CYTO365 AB
• Original Assignee: CYTO365 AB
• Inventors: Tornblom, Micael
• Granted Patent: US 10,960,135 B2
• Time in Patent Office: Days
• CPC Class Codes: A61M 2005/1402 Priming
• CPC Class Codes: A61M 2005/1403 Flushing or purging
• CPC Class Codes: A61M 2039/229 Stopcocks
• CPC Class Codes: A61M 39/223 Multiway valves
• CPC Class Codes: A61M 39/225 Flush valves, i.e. bypass valves for flushing line
• CPC Class Codes: A61M 39/24 Check- or non-return valves
• CPC Class Codes: A61M 5/1407 Infusion of two or more substances
• CPC Class Codes: A61M 5/1409 in series, e.g. first substance passing through container holding second substance, e.g. reconstitution systems needle sets A61M5/162
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407
• CPC Class Codes: A61M 5/16881 Regulating valves on-off valves, e.g. clamps A61M39/28
• CPC Class Codes: F16K 11/085 with cylindrical plug

Abstract

A valve and a method for administering a plurality of drug fluids to a patient are disclosed. For each drug fluid, the valve may be rotated into a selected drug position associated with the drug fluid. With the valve being in the selected drug position, a backpriming may be performed of a connector line of a drug container containing the drug fluid. Thereafter, the drug fluid may be administered with the valve being in the same selected drug position. Thereafter, the valve may be flushed, optionally while maintaining the same selected valve position.

Claims

1. A valve for administering two or more drug fluids, comprising:

a rotational axis,

a housing having;

an inner cavity,

an inner circumferential surface,

one flushing inlet for receiving a flushing fluid, the flushing inlet being fluidly connected to a flushing outlet, which opens into the inner cavity and is positioned on a first level with respect to the rotational axis, and

a plurality of drug inlets, each drug inlet for receiving an associated drug fluid and each drug inlet being fluidly connected to an associated drug outlet opening into the inner cavity and being positioned on a second level that is different from the first level; and

a rotatable valve member having;

an outer circumferential surface,

a main passageway presenting an inlet arranged in the outer circumferential surface at the second level and an outlet arranged coaxially with the rotational axis; and

a transfer channel being located between said first and said second level for carrying the flushing fluid;

wherein, the rotatable valve member is arranged to be rotated into any selected one of a plurality of drug positions, each drug position being associated with a respective one of said drug outlets; and

wherein, in each selected drug position, the drug outlet which is associated with the selected drug position is fluidly connected, simultaneously, to both the inlet of the main passageway and, via the transfer channel, to the flushing outlet.

2. The valve according to claim 1, further comprising a distribution channel for carrying the flushing fluid, and formed at an interface between the housing and the valve member, said distribution channel being circumferentially oriented in relation to the rotational axis and fluidly connected to the flushing outlet;

wherein, the transfer channel of the rotatable valve member is fluidly connected to the distribution channel and extends at least partly in the direction of the rotational axis towards the second level.

3. The valve according to claim 2, wherein, the transfer channel of the rotatable valve member is directly connected within the valve member to the main passageway.

4. The valve according to claim 2,

wherein, the housing further comprises a plurality of flushing recesses formed in the inner circumferential surface of the valve housing, each flushing recess being associated with a selected drug position and extending at least partly in the direction of the rotational axis and being fluidly connected to an associated drug outlet;

and

wherein, in each selected drug position, the drug outlet which is associated with the selected drug position is fluidly connected to the flushing outlet via a flow path formed by the distribution channel, the transfer channel and a flushing recess which is associated with the selected drug position.

5. The valve according to claim 2, wherein the transfer channel has a first end, which is located on the first level and is fluidly connected to the distribution channel, and a second end, which is located adjacent to the second level and which together with the inlet of the main passageway, in each selected drug position, bifurcates a drug outlet associated with the selected drug position.

6. The valve according to claim 2, wherein the distribution channel extends in a circumferential direction over 360 degrees to form a complete annular distribution channel.

7. The valve according to claim 2, wherein the distribution channel extends in a circumferential direction less than 360 degrees to form a partial annular distribution channel.

8. The valve according to claim 1, wherein the valve member is further arranged to be positioned into any selected one of one or more flushing positions;

and

wherein, in each selected flushing position, the inlet of the main passageway is fluidly connected to the flushing outlet via the transfer channel of the rotatable valve member but not to any one of the drug outlets.

9. The valve according to claim 1, wherein the inner circumferential surface of the housing is in sealing engagement with the outer circumferential surface of the valve member.

10. The valve according to claim 1, wherein the inner circumferential surface of the housing and the outer circumferential surface of the valve member are cylindrical.

11. The valve according to claim 1, wherein the inner circumferential surface of the housing and the outer circumferential surface of the valve member are conical or frusto-conical.

12. The valve according to claim 1, wherein the main passageway comprises a first part extending from the inlet of the main passageway towards the rotational axis, and a second part extending coaxially with the rotational axis, from a radially inner end of the first part of the main passageway, towards the outlet of the main passageway.

13. The valve according to claim 1, wherein the plurality of drug positions constitute the only rotary positions of the valve member allowing a drug to be administered from a drug inlet to an outlet of the valve.

14. The valve according to claim 1, wherein the valve member is provided with a handle for rotating the valve member and wherein the first level is located closer to the handle than the second level.

15. The valve according to claim 1, wherein the valve member is provided with a handle for rotating the valve member and wherein the second level is located closer to the handle than the first level.

16. The valve according to claim 1, wherein the valve member is provided with a handle for rotating the valve member, wherein in each selected drug position the handle is aligned with a drug inlet associated with the selected drug position.

17. A valve for administering two or more drug fluids comprising:

an outlet,

a rotational axis,

a housing having;

an inner cavity

an inner circumferential surface,

one flushing inlet for receiving a flushing fluid, the flushing inlet being fluidly connected to a flushing outlet of the housing, which opens into the inner cavity and is positioned on a first level with respect to the rotational axis, and

a plurality of drug inlets, each drug inlet for receiving an associated drug fluid and each drug inlet being fluidly connected to an associated drug outlet opening of the housing into the inner cavity and being positioned on a second level that is different from the first level; and

a rotatable valve member having;

an outer circumferential surface,

a main passageway presenting an inlet arranged in the outer circumferential surface at the second level and an outlet arranged coaxially with the rotational axis; and

a transfer channel being located between said first and said second level for carrying the flushing fluid;

wherein the valve member is arranged to be rotated into any selected one of a plurality of drug positions, each drug position being associated with a respective one of said drug outlets; and

wherein the valve presents simultaneously, in each selected drug position;

a drug flow path extending from the associated drug outlet, through the main passageway, and to the outlet of the valve,

a flushing flow path extending from the flushing outlet to the outlet of the valve and comprising a first part, including the transfer channel, not being common with the drug flow path and a second part, including the main passage way, being common with the drug flow path, and

a backpriming flow path extending from the flushing outlet to the associated drug outlet and being at least partly common with the first part of the flushing flow path.