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Vaccines targeting Pseufomonas aeruginosa

  • US 20190330281A1
  • Filed: 01/05/2018
  • Published: 10/31/2019
  • Est. Priority Date: 01/05/2017
  • Status: Active Grant
First Claim
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1. A polypeptide comprisinga) an amino acid sequence selected from the group consisting of any one of SEQ ID NOs:

  • 11, 1-10, and 12-14, orb) an amino acid sequence consisting of at least or exactly 5 contiguous amino acid residues from any one of SEQ ID NOs;

    11, 1-10, and 12-14, orc) an amino acid sequence having a sequence identity of at least 60% with the amino acid sequence of a),d) an amino acid sequence having a sequence identity of at least 60% with the amino acid sequence of b), ore) an assembly of amino acids derived from any one of SEQ ID NOs;

    11, 1-10, and 12-14 which has essentially the same 3D conformation as in the protein from which said assembly is derived so as to constitute a B-cell epitope,said polypeptide being antigenic in a mammal.

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