METHOD FOR PRODUCING HELPER T CELLS FROM PLURIPOTENT STEM CELLS
First Claim
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1. A method of producing helper T cells comprising:
- (i) culturing T cells, which have been induced from pluripotent stem cells and into which a CD4 gene or a gene product thereof has been introduced, in a medium containing IL-2 and IL-15; and
(ii) isolating CD40L-highly expressing T cells from cells obtained in Step (i).
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Abstract
A method of producing helper T cells, comprising:
- (i) culturing T cells, which have been induced from pluripotent stem cells and into which a CD4 gene or a gene product thereof has been introduced, in a medium containing IL-2 and IL-15; and (ii) isolating CD40L-highly expressing T cells from cells obtained in step (i).
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Citations
18 Claims
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1. A method of producing helper T cells comprising:
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(i) culturing T cells, which have been induced from pluripotent stem cells and into which a CD4 gene or a gene product thereof has been introduced, in a medium containing IL-2 and IL-15; and (ii) isolating CD40L-highly expressing T cells from cells obtained in Step (i). - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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- 13. Helper T cells induced from pluripotent stem cells, the helper T cells comprising CD4-positive CD40L-highly expressing T cells.
Specification