CONTAINER PRECURSOR HAVING A WALL OF GLASS WHICH IS SUPERIMPOSED BY A PLURALITY OF PARTICLES

• US 20200130892A1
• Filed: 10/30/2019
• Published: 04/30/2020
• Est. Priority Date: 10/30/2018
• Status: Active Application

• Current Assignee: Schott AG (Carl-Zeiss-Stiftung), Schott Pharma AG & Company KGaA (Carl-Zeiss-Stiftung)
• Original Assignee: Schott AG (Carl-Zeiss-Stiftung)
• Inventors: Mangold, Stephanie, Heinricht, Frank, Rudigier-Voigt, Eveline, Anton, Andrea
• Application Number:
  US16/668,016
• Publication Number:
  US 20200130892A1
• Time in Patent Office: Days
• CPC Class Codes: A61J 1/065 Rigid ampoules, e.g. glass ampoules
• CPC Class Codes: A61J 1/1406 Septums, pierceable membranes
• CPC Class Codes: A61J 1/1468 Containers characterised by specific material properties
• CPC Class Codes: A61J 1/16 Holders for containers
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: B32B 2264/0214 Particles made of materials belonging to B32B27/00
• CPC Class Codes: B32B 2264/1022 Titania
• CPC Class Codes: B32B 2264/1023 Alumina
• CPC Class Codes: B32B 2264/305 Particle size distribution, e.g. unimodal size distribution
• CPC Class Codes: B32B 2264/308 Aspect ratio of particles
• CPC Class Codes: B32B 5/16 characterised by features of a layer formed of particles, e.g. chips, powder or granules layer formed of natural mineral particles B32B19/00; layer being formed of wood fibres, chips or particles B32B21/02
• CPC Class Codes: B65D 23/0807 Coatings
• CPC Class Codes: B65D 23/0814 characterised by the composition of the material
• CPC Class Codes: B65D 25/14 Linings or internal coatings of containers made by folding or erecting blanks made of paper B65D5/56 ; linings for domestic water storage heaters F24H1/183
• CPC Class Codes: B65D 25/34 Coverings or external coatings of containers made by folding or erecting blanks made of paper B65D5/62; for bottles or jars B65D23/08; wrappers B65D65/00
• CPC Class Codes: C03C 17/005 Coating the outside
• CPC Class Codes: C03C 17/007 containing a dispersed phase, e.g. particles, fibres or flakes, in a continuous phase
• CPC Class Codes: C03C 17/30 with silicon-containing compounds
• CPC Class Codes: C03C 2217/42 consisting of particles only
• CPC Class Codes: C03C 2217/70 Properties of coatings
• CPC Class Codes: C03C 2217/75 : Hydrophilic and oleophilic coatings

Abstract

Container precursors are provided that have a wall of glass. The wall of glass at least partially encloses an interior volume. The wall of glass has a side that faces away from the interior volume. The side is at least partially superimposed by a plurality of particles. An arrangement is also provided that includes a packaging and a multitude of the container precursors. A process for preparing a functionalised container precursor is also provided. A process for packaging pharmaceutical compositions and closed containers obtainable by this process are provided.

Claims

1. A container precursor comprising:

a wall of glass at least partially enclosing an interior volume; and

a plurality of particles at least partially superimposing a side of the wall of glass that faces away from the interior volume.

2. The container precursor of claim 1, wherein the plurality of particles superimposes at least 10% of the side of the wall of glass that faces away from the interior volume.

3. The container precursor of claim 1, wherein the plurality of particles superimposes 1 to 50% of the side of the wall of glass that faces away from the interior volume.

4. The container precursor of claim 1, wherein the side of the wall of glass that faces away from the interior volume has a coefficient of dry sliding friction of less than 0.25.

5. The container precursor of claim 1, wherein the plurality of particles is across between at least 10% and a full surface area of the side of the wall of glass that faces away from the interior volume.

6. The container precursor of claim 1, wherein the side of the wall of glass that faces away from the interior volume has a contact angle for wetting with water of 0 to 45°

.

7. The container precursor of claim 1, wherein the wall of glass comprises a side that faces the interior volume that is not superimposed by any of the plurality of particles.

8. A container comprising:

a wall of glass that forms a hollow glass body at least partially enclosing an interior volume, wherein the hollow glass body comprises, in a direction of a length of the hollow glass body, a first end region, a body region, and a further end region;

a plurality of particles at least partially superimposing a side of the wall of glass that faces away from the interior volume in the body region,

wherein, in the first end region and/or in the further end region, the side of the wall of glass that faces away from the interior volume is not superimposed by any of the plurality of particles.

9. The container of claim 8, wherein the body region has a first coefficient of dry sliding friction at the side of the wall of glass that faces away from the interior volume, the first end region has a second coefficient of static friction, and the further end region has a third coefficient of static friction, the container further comprising a ratio of the first coefficient of dry sliding friction to the second coefficient of static friction and/or to the third coefficient of static friction in a range from 0.01 to 0.9;

and

wherein the second and/or third coefficient of static friction is at least 0.15.

10. The container of claim 8, further comprising a closure closing the interior volume and a pharmaceutical composition in the interior volume.

11. The container of claim 8, wherein the particles of the plurality of particles are directly joined to the wall of glass via Van-der-Waals forces, but not via covalent bonds.

12. The container of claim 8, wherein the wall of glass comprises a side that faces the interior volume that is not superimposed by any of the plurality of particles.

13. The container of claim 8, wherein the plurality of particles comprise a particle size distribution selected from a group consisting of a D₅₀ in a range from 1 to 100 μ

m, a D₁₀ in a range from 0.1 to 50 μ

m, a D₉₀ in a range from 0.5 to 100 μ

m, a full width at half maximum (FWHM) which is less than 30%, and combinations thereof.

14. The container of claim 8, wherein the plurality of particles have a decomposition temperature of between more than 500°

C. and 2,000°

C.

15. The container of claim 14, wherein the decomposition temperature is more than 1,400°

C.

16. The container of claim 8, wherein the plurality of particles comprise a material selected from a group consisting of a boron nitride, a molybdenum sulphide, a silicon nitride, an oxide, MoS₂, Si₃N₄, silicon oxide, titanium oxide, SiO₂, TiO₂, siloxane, a silane, organo-silane, latex, silicone resin, hybridpolymer silane, a hybridpolymer siloxane, polyorganosiloxane, polyalkylsiloxane, polysilsesquioxane, inorganic silane,

17. The container of claim 8, wherein the particles of the plurality of particles are not embedded in any material.

18. The container of claim 8, wherein the plurality of particles have an aspect ratio in a range from 0.5 to 1.5.

19. The container of claim 8, wherein the wall of glass has a transmission of light of a wavelength in a range from 400 nm to 2300 nm of more than 0.7.

20. An arrangement comprising:

a packaging; and

a plurality of containers of claim 8 packaged in the packaging.

21. A process for preparing a functionalised container precursor, comprising:

providing a wall of glass that at least partially encloses an interior volume;

superimposing at least a part of the wall of glass on a side of the wall of glass that faces away from the interior volume with a composition, the composition comprising a first plurality of particles and a vehicle; and

decreasing a proportion of the vehicle in the composition, thereby leaving the first plurality of particles and/or particles obtained from the first plurality of particles superimposed on the wall of glass.